Spectinomycin dihydrochloride pentahydrate
Empirical Formula (Hill Notation): | C14H24N2O7 · 2HCl · 5H2O |
CAS Number: | 22189-32-8 |
Molecular Weight: | 495.35 |
Beilstein/REAXYS Number: | 5684150 |
EC Number: | 244-554-3 |
MDL number: | MFCD00150886 |
PubChem Substance ID: | 329757229 |
NACRES: | NA.24 |
Кат. номер |
46738-VAR |
46738-250MG |
46738-1EA |
Chemical structure: aminoglycoside
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Spectinomycin is an aminocyclitol antibiotic derived from
Streptomyces spectabilis. It has been shown to have a wide variety of uses, including treating acute gonorrheal urethritis and cervictis, to mark cell layers to monitor cell fate during leaf development, as a selection marker in plant related transformation systems for plant cells containing the marker gene Spcr, to study respiratory tract infections of cattle caused by
Pasteurella multocida and
Mannheimia haemolytica, and to generate plants deficient for the plastid-encoded RNA polymerase on MS-agar media. Spectinomycin also has use in amplification of low copy number plasmid carrying replicons. It is recommended for use in cell culture applications at 7.5-20 mg/L.
Spectinomycin dihydrochloride pentahydrate may be used as a reference standard for the determination of spectinomycin in bovine milk samples by liquid chromatography with electrochemical detection.
Solutions can be stored at 2-8°C for several weeks or at -20°C for more extended periods.
Stock solutions should be prepared at 10 mg/mL in water and filter sterilized.
VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH
Quality Level | 100 |
grade | analytical standard |
product line | VETRANAL® |
form | neat |
shelf life | limited shelf life, expiry date on the label |
application(s) | HPLC: suitable, gas chromatography (GC): suitable |
solubility | H2O: soluble at |
Featured Industry | Clinical Forensics and Toxicology Pharmaceutical (small molecule) |
Mode of action | protein synthesis | interferes |
antibiotic activity spectrum | Gram-negative bacteria, Gram-positive bacteria |
format | neat |
storage temp. | 2-8°C |
SMILES string | Cl[H].Cl[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H][C@@]12O[C@H](C)CC(=O)[C@]1(O)O[C@]3([H])[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@@]3([H])O2 |
InChI | 1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1 |
InChI key | DCHJOVNPPSBWHK-UXXUFHFZSA-N |
pictograms | GHS07 |
signalword | Warning |
hcodes | H315 - H319 - H335 |
pcodes | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
Target Organs | Respiratory system |
Personal Protective Equipment | Eyeshields, Gloves, type N95 (US) |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point F | Not applicable |
Flash Point C | Not applicable |