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AEA-d11
Empirical Formula (Hill Notation): C22H26D11NO2 CAS Number: 2260669-86-9 Molecular Weight: 358.60
Кат. номер 857466W-500UG 857466W-1MG General descriptionAnandamide (AEA) is an agonist of the cannabinoid and non-cannabinoid receptors. It is an N-acyl ethanolamide derivative of C20:4 fatty acid, which is also known as arachidonic acid. AEA is a lipid neurotransmitter synthesized and released by the brain nerve cells as well as macrophages.Biochem/physiol ActionsAnandamide (AEA) is involved in many physiological and pathophysiological functions, such as regulation of energy consumption and balance. It is also involved in initiation and control of inflammation and modulatory effects on sensory and autonomic nerve signaling.Packaging2 mL Amber Glass Sealed Ampule (857466W-1mg)
2 mL Amber Glass Sealed Ampule (857466W-500ug)Параметрыassay >99% (TLC) form methanol solution packaging pkg of 1 x 1 mL (857466W-500ug), pkg of 2 x 1 mL (857466W-1mg) Торговая марка Avanti Polar Lipids concentration 0.5 mg/mL (857466W-1mg), 0.5 mg/mL (857466W-500ug) shipped in dry ice storage temp. −20°C SMILES string O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\C([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])NCCO
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H370 pcodes P210 - P280 - P302 + P352 + P312 - P304 + P340 + P311 - P370 + P378 - P403 + P235 RIDADR UN1230 - class 3 - PG 2 - Methanol, solution Flash Point F 49.5 °F - closed cup Flash Point C 9.7 °C - closed cup Узнать цену -
AEA-d4 857465W-1MG
Empirical Formula (Hill Notation): C22H33 D4NO2 Molecular Weight: 351.56 NACRES: NA.25 General descriptionAnandamide (N-arachidonoyl ethanolamine, NArE, AEA) belongs to a large family of amidated signaling lipids, the N-acyl ethanolamines (NAEs). C20:4 AEA is a 20 carbon length side chain with four double bonds, i.e. the arachidonoyl group in AEA.Biochem/physiol ActionsAnandamide (N-arachidonoyl ethanolamine, NArE, AEA) is a receptor for cannabinoid receptor. AEA functions as a mediator for many physiological processes including inflammation, pain, and appetite. C20:4 AEA is capable of activating vanilloid receptor (VR).Packaging2 mL Amber Glass Sealed Ampule (857465W-1mg)Параметрыassay >99% (TLC) form methanol solution packaging pkg of 1 x 1 mL (857465W-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (857465W-1mg) shipped in dry ice storage temp. −20°C SMILES string O=C(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)NC([2H])([2H])C([2H])([2H])O
Safety Informationpictograms GHS02,GHS06,GHS08 signalword Danger hcodes H225 - H301 + H311 + H331 - H370 pcodes P210 - P280 - P302 + P352 + P312 - P304 + P340 + P311 - P370 + P378 - P403 + P235 RIDADR UN1230 - class 3 - PG 2 - Methanol, solution Flash Point F 49.5 °F - closed cup Flash Point C 9.7 °C - closed cup Узнать цену -
alkyne-cholesterol
Empirical Formula (Hill Notation): C26H40O CAS Number: 1631985-09-5 Molecular Weight: 368.60
Кат. номер 700146P-250UG 700146P-100UG General descriptionAlkyne-cholesterol is a clickable cholesterol probe proprietary for Avanti Polar Lipids. They differ from cholesterol by having an alkyne group.
This reagent is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry, in the presence of a copper (Cu)-containing catalyst.Biochem/physiol ActionsAlkyne-cholesterol is not applicable for use in living cells due to copper ion (Cu (I) and Cu (II)) requirements. It aids in easy and sensitive detection of cholesterol using various biophysical methods. Alkyne-cholesterol can be conjugated to boron-dipyrromethene (BODIPY) fluorescent dye. It is useful in cholesterol trafficking studies in various organelles including mitochondria, endoplasmic reticulum and Golgi.Packaging5 mL Amber Glass Screw Cap Vial (700146P-250ug)
5 mL Amber Glass Screw Cap Vial (700146P-100ug)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 100 μg (700146P-100ug), pkg of 1 x 250 μg (700146P-250ug) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
Allocholic acid 700213P-5MG
Empirical Formula (Hill Notation): C24H40O5 Molecular Weight: 408.57 Packaging5 mL Amber Glass Screw Cap Vial (700213P-5MG)Параметрыassay >99% (TLC) form powder packaging package of 1 x 5 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Alloisolithocholic acid 700196P-10MG
Empirical Formula (Hill Notation): C24H40O3 Molecular Weight: 376.57 Packaging5 mL Amber Glass Screw Cap Vial (700196P-10MG)Параметрыassay >99% (TLC) form powder packaging package of 1 x 10 mg (pkg of 1 x10mg (700196P-10mg)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)[C@@]3([H])CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(O)=O
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Apocholic acid 700241P-5MG
Empirical Formula (Hill Notation): C24H38O4 Molecular Weight: 390.56 Packaging5 mL Amber Glass Screw Cap Vial (700241P-5MG)Параметрыassay >99% (TLC) form powder packaging package of 1 x 5 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Apocholic acid (Delta 14 isomer) 700289P-1MG
Empirical Formula (Hill Notation): C24H38O4 Molecular Weight: 390.56 Packaging5 mL Amber Glass Screw Cap Vial (700289P-1mg)Параметрыassay >99% (TLC) form powder packaging package of 1 x 1 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string C[C@]12[C@@H](O)C[C@@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])CC4)([H])C4C1=CC[C@]2([H])[C@]([H])(C)CCC(O)=O
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
arachidonic acid-alkyne 900411E-1MG
Empirical Formula (Hill Notation): C20H28O2 CAS Number: 1219038-32-0 Molecular Weight: 300.44 NACRES: NA.25 General descriptionArachidonic acid (ARA) is a polyunsaturated ω-6 fatty acid. It is composed of 20-carbon chain fatty acid. ARA is found in fish, eggs, poultry and sea food. It is present abundantly in phospholipids of cell membranes.Biochem/physiol ActionsArachidonic acid (ARA) governs the cell membrane fluidity and ion channels activity. Accumulation of free ARA leads to cytotoxicity followed by cell death.Packaging5 mL Amber Screw Cap Bottle with Foil Bag Argon Overseal (900411E-1mg)Параметрыform ethanol solution packaging pkg of 1 x 1 mL (900411E-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (900411E-1mg) shipped in dry ice storage temp. −20°C
Safety Informationpictograms GHS02,GHS07 signalword Danger hcodes H225 - H319 pcodes P210 - P305 + P351 + P338 - P370 + P378 - P403 + P235 RIDADR UN1170 - class 3 - PG 2 - Ethanol, solution WGK Germany WGK 3 Flash Point F 55.4 °F - closed cup Flash Point C 13.0 °C - closed cup Узнать цену -
arachidonic acid-d11 861810E-1MG
Empirical Formula (Hill Notation): C20H21D11O2 CAS Number: 1287387-84-1 Molecular Weight: 315.53 NACRES: NA.25 General descriptionArachidonic acid (ARA) is a polyunsaturated -6 fatty acid. It contains 20-carbon fatty acid chain along with four methylene- interrupted cis double bonds. ARA is present abundantly in phospholipids of cell membranes. It can be acquired from dietary sources.ApplicationArachidonic acid-d11 has been used in sobetiramides (Sob-AM2) quantification by liquid chromatography-mass spectrometry (LC-MS) method.Biochem/physiol ActionsArachidonic acid (ARA) governs the cell membrane fluidity and ion channels activity. Accumulation of free ARA leads to cytotoxicity followed by cell death.Packaging5 mL Amber Screw Cap Bottle with Foil Bag Argon Overseal (861810E-1mg)Параметрыform ethanol solution packaging pkg of 1 x 1 mL (861810E-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (861810E-1mg) shipped in dry ice storage temp. −70°C
Safety Informationpictograms GHS02,GHS07 signalword Danger hcodes H225 - H319 pcodes P210 - P305 + P351 + P338 RIDADR UN1170 - class 3 - PG 2 - Ethanol, solution WGK Germany WGK 1 Flash Point F 55.4 °F - closed cup Flash Point C 13.0 °C - closed cup Узнать цену -
Atheronal A 700088P-1MG
Empirical Formula (Hill Notation): C27H46O3 Molecular Weight: 418.65 NACRES: NA.25 General descriptionAtheronal A is a product of cholesterol ozonolysis. It is produced in the neutrophils post oxidative burst. Atheronal A displays higher hydrophilicity than cholesterol.
Atheronal molecules may be a new association, in the already complex inter-relationship, between inflammation, cholesterol oxidation, the tissue macrophage, and atherosclerosis.Biochem/physiol ActionsAtheronal A favors apoptosis and is implicated in atherosclerosis. It promotes neuronal cell death, β- amyloid aggregation and chemotaxis in macrophages. Atheronal A modulates phosphatidylethanolamine membrane structure and MAPKs (mitogen activated protein kinase) functionality.Packaging5 mL Amber Glass Screw Cap Vial (700088P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (700088P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −70°C SMILES string C[C@]1(CC2)C(CCC1C(CCCC(C)C)C)C(C2[C@](CC[C@H](O)C3)(C)C3=O)CC=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F No data available Flash Point C No data available Узнать цену -
Atheronal B 700089P-1MG
Empirical Formula (Hill Notation): C27H46O3 Molecular Weight: 418.65 NACRES: NA.25 General descriptionAtheronal-B is generated by the intramolecular aldolization of atheronal-A and this interconversion is rapid. It is present in plasma and is well detectable. Atheronal A and B are also referred to as cholesterol 5,6-secosterols.
Atheronal molecules may be a new association, in the already complex inter-relationship, between inflammation, cholesterol oxidation, the tissue macrophage, and atherosclerosis.Biochem/physiol ActionsAtheronal-B levels are elevated in patients with cardiovascular disease like atherosclerosis. Atheronal A and B favor misfolding of α-synuclein, apolipoprotein-B100 and β-amyloid by adding an aldehyde group to the lysine side chain. In addition, atheronals also modify the cationic property of myelin basic protein (MBP) leading to structural change, which contributes directly to the pathogenesis of multiple sclerosis.Packaging5 mL Amber Glass Screw Cap Vial (700089P-1mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (700089P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F No data available Flash Point C No data available Узнать цену -
Aurora®-DSG 550001P-500UG
Empirical Formula (Hill Notation): Au55C262H265P12NO7 Molecular Weight: 14744.75 NACRES: NA.25 General descriptionThis new conjugate from Avanti consists of an Aurora® gold cluster capped with triphenylphosphine ligands and a single diglyceride ligand. Fifty-five gold atom nanoparticles, first described by Schmid, are fascinating structures that are commonly used for contrast agents in various imaging applications. Ideally this particle, unlike larger colloidal style particles, is less intrusive to the target application and behaves like an organic entity instead of a foreign metallic probe. They also are a great generic platform for bottom up synthesis of novel, gold-centered nanostructures due to the ease and completeness of ligand exchange reactions. This complex is readily visible under TEM and can also be viewed in optical microscopes if further processed using a silver development procedure.Biochem/physiol ActionsAurora®-DSG (Distearoylglycerol) nanoparticles aid in improving contrast in liposome and membrane preparations in cryo-transmission microscopy imaging. They are useful in lipid research as they provide good resolution image of the lipid bilayer on incorporation. Their biophysical interaction with lipid bilayers is exploited in many membrane research studies. Confocal, atomic force and high-resolution microscopy utilize the incorporation of Aurora® into the heterogeneous bilayers, as they do not hamper the lipid layer properties and composition.Packaging5 mL PTFE Vial with Screw Cap (550001P-500ug)Legal InformationAurora is a registered trademark of Avanti Polar Lipids, Inc.Параметрыassay >95% (TLC) form powder packaging pkg of 1 x 500 µg (with screw cap) Торговая марка Avanti Polar Lipids shipped in wet ice storage temp. 2-8°C
Safety Informationpictograms GHS07,GHS08 signalword Warning hcodes H317 - H373 pcodes P260 - P280 - P314 - P333 + P313 - P362 + P364 - P501 Target Organs Nervous system RIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Aurora®-PLC
NACRES: NA.25
Кат. номер 550002P-10MG 550002P-100MG General description3-5nm gold nanoparticle stabilized with dodecanethiol, coated with 1-myristoyl-sn-glycero-3-phosphocholine
Aurora® nanoparticles from Avanti are useful in high resolution liposome imaging studies. It also enables identification and quantification of lipid species. Aurora®-PLC gold nanoparticle is stabilized with dodecanethiol, coated with 1-myristoyl-sn-glycero-3-phosphocholine.Packaging5 mL PTFE Vial with Screw Cap (550002P-10mg)
5 mL PTFE Vial with Screw Cap (550002P-100mg)Legal InformationAurora is a registered trademark of Avanti Polar Lipids, Inc.Параметрыassay >95% (TLC) form powder packaging pkg of 1 x 10 mg (with screw cap (550002P-10mg)), pkg of 1 x 100 mg (with screw cap (550002P-100mg)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety Informationpictograms GHS05,GHS07,GHS09 signalword Danger hcodes H314 - H317 - H411 pcodes P260 - P272 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 RIDADR UN 1759 8 / PGIII WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Azelaoyl-PAF 870601P-1MG
Empirical Formula (Hill Notation): C33H66NO9P CAS Number: 354583-69-0 Molecular Weight: 651.85 NACRES: NA.25 ApplicationAzelaoyl-PAF may be used to study its binding affinity with 4F or 2F anti-inflammatory peptides.Biochem/physiol ActionsAzelaoyl-PAF (1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine) is a low molecular weight alkyl phosphatidylcholine. It is a constituent of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF serves as a high affinity ligand and agonist for peroxisome proliferator-activated receptor- (PPAR).Packaging5 mL Clear Glass Sealed Ampule (870601P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (870601P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
Azelaoyl-PAF 870601C-1MG
Empirical Formula (Hill Notation): C33H66NO9P CAS Number: 354583-69-0 Molecular Weight: 651.85 NACRES: NA.25 General description1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles. Azelaoyl-PAF is a low molecular weight phospholipid.ApplicationAzelaoyl-PAF may be used in binding assay of anti-inflammatory peptides, 2F and 4F.Biochem/physiol Actions1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine (Azelaoyl-PAF) acts as an agonist for peroxisome proliferator-activated receptors (PPAR-). It may be used as a therapeutic for Friedreichs ataxia (FRDA). At low concentrations azelaoyl-PAF may induce apoptosis.Packaging5 mL Clear Glass Sealed Ampule (870601C-1mg)Параметрыpackaging pkg of 1 x 1 mL (870601C-1mg) Торговая марка Avanti Polar Lipids concentration 1 mg/mL (870601C-1mg) shipped in dry ice storage temp. 20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC)=O
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
Azido sphingosine (d14:1) 860760P-1MG
Empirical Formula (Hill Notation): C14H28N4O2 Molecular Weight: 284.40 Packaging5 mL Amber Glass Screw Cap Vial (860760P-1MG)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Azido-PEG2000-Carboxy 880225P-100MG
Empirical Formula (Hill Notation): C90H179N3O46 Molecular Weight: 2039.38 Packaging5 mL Amber Glass Screw Cap Vial (880225P-100MG)Параметрыassay >99% (TLC) form powder Торговая марка Avanti Polar Lipids packaging pkg of (pkg of 1 X 100 mg (880225P-100MG)) shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Azo Coenzyme A
Empirical Formula (Hill Notation): C41H67N12O17P3S CAS Number: 2260670-58-2 Molecular Weight: 1125.03 NACRES: NA.25
Кат. номер 870624P-5MG 870624P-1MG Packaging5 mL Amber Glass Screw Cap VialПараметрыform powder packaging 1 ea of 1 mg (870624P-1mg), 1 ea of 5 mg (870624P-5mg) Торговая марка Avanti Polar Lipids application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. 20°C SMILES string O[C@@](C(NCCC(NCCSC(CCCC1=CC=C(/N=N/C2=CC=C(CCCC)C=C2)C=C1)=O)=O)=O)(C(C)(COP([O-])(OP([O-])(OC[C@H]([C@H]3OP([O-])(O)=O)O[C@H]([C@@H]3O)N4C5=C(C(N)=NC=N5)N=C4)=O)=O)C)[H].[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Azo Lyso PA
Empirical Formula (Hill Notation): C23H34N3O7P Molecular Weight: 495.51
Кат. номер 870626P-5MG 870626P-25MG Packaging5 mL Amber Glass Screw Cap Vial (870626E-5MG)
5 mL Amber Glass Screw Cap Vial (870626E-25MG)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 25 mg, pkg of 1 x 5 mg Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string OP(OC[C@]([H])(O)COC(CCCC1=CC=C(/N=N/C2=CC=C(CCCC)C=C2)C=C1)=O)([O-])=O.[NH4+]
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
BbGL-1 700193P-1MG
Empirical Formula (Hill Notation): C49H86O7 Molecular Weight: 787.20 Packaging5 mL Amber Glass Screw Cap Vial (700193P-1MG)Параметрыform powder packaging package of 1 x 1 mg Торговая марка Avanti Polar Lipids application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
BbGL-2 840528P-1MG
Empirical Formula (Hill Notation): C43H80O10 Molecular Weight: 757.09 Packaging5 mL Amber Glass Screw Cap Vial (840528P-1MG)Параметрыform powder packaging package of 1 x 1 mg Торговая марка Avanti Polar Lipids application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. −20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Bicelle Blend (DMPC:DHPC (2.8:1, mol:mol)) 790590P-200MG
NACRES: NA.25 General descriptionThe bicelle blend is designed to aid with the production of high-quality membrane protein crystals. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Reference/Protocol: https://avantilipids.com/tech-support/liposome-preparation/bicelle-preparation/
Bicelle blend contains 200mg of dimyristoylphosphatidylcholine (DMPC): dihexanoylphosphatidylcholine (DHPC) Pre-Mixed Bicelle (2.8:1, mol:mol). Bicelle is a discoidal lipid aggregate. It is made up of long-chain phospholipid and a detergent. The planar bilayer is generally composed of DMPC, which may have phospholipids with identical chain lengths but differ in the head group. The detergent layer is composed of a short-chain phospholipid like DHPC.Biochem/physiol ActionsBicelles are used as membrane mimetics for studying membrane-associated biomolecules.Packaging5ML Amber Glass Screw Cap Vial (790590P-200MG)Параметрыform powder packaging pkg of 2 x 100 mg (790590P-200MG) Торговая марка Avanti Polar Lipids application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. 20°C
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Bicelle Kit 850563P-1EA
General descriptionThe bicelle kit is designed to aid with the production of high-quality membrane protein crystals. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.
Bicelle kit contains 200mg of dimyristoylphosphatidylcholine (DMPC), 200mg of dimyristoylphosphatidylglycerol (DMPG), 1g of 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate (CHAPS) and 1g of 3-(cholamidopropyl)dimethylammonio-2-hydroxy-1-propane-sulfonate (CHAPSO). Bicelle is a discoidal lipid aggregate. A bicelle consists of a planar bilayer at the center made of long-chain phospholipids, which are encircled by a detergent layer. The planar bilayer is generally composed of DMPC, which may have phospholipids such as (DMPG) for alteration of charge of the membrane. The detergent layer is composed of bile salt derivative, such as CHAPSO.Biochem/physiol ActionsBicelles acts as membrane mimetics and facilitate membrane-associated biomolecules study.PackagingPackage contains 200MG of DMPC, 200MG of DMPG, 1G of CHAPS, and 1G of CHAPSO
20ML Clear Glass Screw Cap Vial for each component (850563P-1EA)Параметрыform powder Торговая марка Avanti Polar Lipids application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. −20°C Узнать цену -
Biotin S1P 860552P-100UG
Empirical Formula (Hill Notation): C28H53N4O7PS CAS Number: 799812-63-8 Molecular Weight: 620.78 NACRES: NA.25 General descriptionBiotinylated sphingosine 1-phosphate (Biotin S1P) is produced by the phosphorylation of biotinyl sphingosine by recombinant human sphingosine kinase 1 and 2 (hSK1 and hSK2). Biotinyl sphingosine is derived from sphingosine and it contains a biotin unit at the ω-terminal of its fatty-acid chain.ApplicationBiotinylated sphingosine 1-phosphate (Biotin S1P) is suitable to be used as an antigen to preabsorb murine monoclonal antibody, LT1002.Packaging2 mL Amber Serum Vial with Stopper and Crimp Cap (860552P-100ug)Параметрыform powder packaging pkg of 1 x 100 µg (with stopper and crimp cap (860552P-100ug)) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@]1(CCCCC(NCCCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O)=O)SC[C@@]2([H])[C@]1([H])NC(N2)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
Biotin Sphingosine 860550P-1MG
Empirical Formula (Hill Notation): C28H52N4O4S CAS Number: 752987-57-8 Molecular Weight: 540.80 General descriptionBiotin Sphingosine is a derivative of sphingosine. It contains a biotin moiety linked to the ω-terminal of its fatty-acid chain.ApplicationBiotin Sphingosine has been used as a substrate in sphingosine kinases (SphK) assay. It has also been used to label wt- ceramide synthase 1 (CerS1) expressed in UM-SCC-22A cells, to study the interaction between CerS1-generated C18-ceramide and light chain 3 (LC3B).Biochem/physiol ActionsBiotin Sphingosineplays a vital role in identifying sphingosine interaction with acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A).Packaging5 mL Amber Glass Screw Cap Vial (860550P-1mg)Параметрыform powder packaging pkg of 1 x 1 mg (860550P-1mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@]1(CCCCC(NCCCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@](N)([H])CO)=O)SC[C@@]2([H])[C@]1([H])NC(N2)=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
bis(14:0 PE)-DTPA (Gd) 791297P-5MG
Empirical Formula (Hill Notation): C80H154GdN7O24P2 Molecular Weight: 1817.31 NACRES: NA.25 General descriptionbis(14:0 PE)-DTPA (Gd) is a lipidic gadolinium complex, with four units of myristic acid. The diethylenetriaminepentaacetic acid is chelated to gadolinium ion.Applicationbis(14:0 PE)-DTPA (Gd)(bis(1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine)-N-N-diethylenetriaminepentaacetic acid (gadolinium salt)) has been used in liposome preparation for magnetic resonance imaging (MRI) measurements.
bis(14:0 PE)-DTPA (Gd) has been used in liposome preparation.Biochem/physiol ActionsGadolinium based lipid complexes are contrast agents in magnetic resonance imaging. Such lipid complexes are used in liposome-based bilayer preparation for imaging.Packaging5 mL Amber Glass Screw Cap Vial (791297P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (791297P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
bis(16:0 PE)-DTPA (Gd) 791298P-5MG
Empirical Formula (Hill Notation): C88H170GdN7O24P2 Molecular Weight: 1929.52 General descriptionbis(16:0 PE)-DTPA (Gd) (bis(1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine)-N-N-diethylenetriaminepentaacetic acid (gadolinium salt)) is a lipidic gadolinium complex, with four units of palmitic acid. The diethylenetriaminepentaacetic acid (DTPA) is chelated to gadolinium ion.Biochem/physiol ActionsGadolinium (Gd) has magnetic moment property and is potent magnetic resonance imaging (MRI) contrast agent. Diethylenetriaminepentaacetic acid attached to phosphatidylethanolamine (DTPA-PE) conjugated with Gd to form vesicles or liposomes improves the relaxivity of the Gd-DTPA complex while imaging. Targeted liposomes with Gd-DTPA (gadolinium-diethylenetriamine pentaacetic acid) facilitate tumor visualization and imaging.Packaging5 mL Amber Glass Screw Cap Vial (791298P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (791298P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
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bis(18:0 PE)-DTPA (Gd) 791299P-5MG
Empirical Formula (Hill Notation): C96H186GdN7O24P2 Molecular Weight: 2041.73 NACRES: NA.25 General descriptionbis(1,2-distearoyl-sn-glycero-3-phosphoethanolamine)-N-N-diethylenetriaminepentaacetic acid (gadolinium salt) or bis(18:0 PE)-DTPA (Gd) comprises four copies of stearic acid. It has DTPA in the head group of ethanolamine. The DTPA is attached to gadolinium ion.Biochem/physiol ActionsGadolinium salt based DTPA conjugated phospholipid is useful in magnetic resonance imaging (MRI) and multimodal imaging. Apart from being an MRI contrast agent, PE-DTPA (Gd) liposome is also flexible for modification for binding different targets using copper–free click–chemistry methodology.Packaging5 mL Amber Glass Screw Cap Vial (791299P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (791299P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
Bis-DSPE PEG2000 880133P-25MG
Empirical Formula (Hill Notation): C172H336N2Na2O62P2 Molecular Weight: 3532.41 NACRES: NA.25 Packaging5 mL Amber Glass Screw Cap Vial (880133P-25mg)Параметрыform powder packaging pkg of 1 x 25 mg (880133P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@@](COP([O-])(OCCNC(COCCOCCOCCOCC(NCCOP([O-])(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+].[Na+]
Safety InformationRIDADR NONH for all modes of transport Flash Point F No data available Flash Point C No data available Узнать цену -
BMP Snoopers® 330502-5EA
NACRES: NA.62 General descriptionAvanti BMP Snoopers® consist of 9 different lipid species spotted individually on a solid support. Each spot contains 1 µg of the highest quality pure lipid and is ideal for investigating lipid-protein interactions.PackagingMembrane Packaged in Foil Pouch (330502-5EA)Legal InformationSnoopers is a registered trademark of Avanti Polar Lipids, Inc.ПараметрыТорговая марка Avanti Polar Lipids packaging 1 ea of 5 x (membrane packaged in foil pouch) shipped in wet ice storage temp. 2-8°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
BMP22
Empirical Formula (Hill Notation): C22H39O3P Molecular Weight: 382.52
Кат. номер 870865P-5MG 870865P-1MG General descriptionBMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.Biochem/physiol ActionsBMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.Packaging5ML Glass Amber Screw Cap Vial (870865P-5MG)
5ML Glass Amber Screw Cap Vial (870865P-1MG)Параметрыform powder packaging pkg of 1 x 1 mg (870865P-1mg), pkg of 1 x 5 mg (870865P-5mg) Торговая марка Avanti Polar Lipids application(s) thin layer chromatography (TLC): 99% shipped in dry ice storage temp. 20°C SMILES string CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1
Safety InformationWGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Brain CPE
Empirical Formula (Hill Notation): C38H77N2O6P CAS Number: 112130-78-6 Molecular Weight: 689.00 NACRES: NA.25
Кат. номер 860066P-25MG 860066P-5MG General descriptionCeramide phosphoethanolamine (CPE) is a sphingolipid found in mammalian cells, bacteria and invertebrates. It is a major sphingolipid found in the cell membrane of Drosophila and Musca. A high level of CPE is observed in mammalian brain and testis and lower levels in liver and heart. CPE is a precursor for the production of sphingomyelin in the liver.Packaging5 mL Clear Glass Sealed Ampule (860066P-25mg)
5 mL Clear Glass Sealed Ampule (860066P-5mg)Параметрыform powder packaging pkg of 1 x 25 mg (860066P-25mg), pkg of 1 x 5 mg (860066P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)COP([O-])(OCC[NH3+])=O
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Brain Extract Polar
CAS Number: 86088-88-2 NACRES: NA.25
Кат. номер 141101P-500MG 141101P-100MG General descriptionBrain Extract Polar comprises phosphatidylethanolamine as a major lipid component. It also contains phosphatidylserine and phosphatidylcholine. The minor components include the phosphatidic acid and phosphatidylinositol.
Brain Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.ApplicationBrain Extract Polar has been used in parallel artificial membrane permeability assay (PAMPA) for coating membrane to evaluate blood brain-barrier permeability, and for drug permeability studies.Biochem/physiol ActionsLipid extracts from the mammalian tissues like brain, kidney and liver are used in generating model membranes for mimicking real membranes. Brain lipid, especially the polar fraction play a key role in the inhibition of prion seeded amyloid formation.Packaging5 mL Clear Glass Sealed Ampule (141101P-500mg)
5 mL Clear Glass Sealed Ampule (141101P-100mg)Параметрыform powder packaging pkg of 1 x 100 mg (141101P-100mg), pkg of 5 x 100 mg (141101P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
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Brain Extract Total
CAS Number: 86088-88-2 NACRES: NA.25
Кат. номер 131101P-1G 131101P-100MG General descriptionTotal Lipid Extract is a chloroform:methanol extract of the respective tissue (Brain, Soybean, Heart, etc.). This extract is partitioned against deionized water, and the chloroform phase is concentrated.ApplicationBrain extract total has been used for the preparation of liposomes. It has also been used as a component of lipid cocktail for lipid cosedimentation assay.Packaging60 mL Amber Wide Mouth Screw Cap Glass Bottle (131101P-1g)
5 mL Clear Glass Sealed Ampule (131101P-100mg)Параметрыform powder packaging pkg of 1 x 1 g (131101P-1g), pkg of 1 x 100 mg (131101P-100mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C
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Brain Lyso PE 850095P-10MG
CAS Number: 475995-55-2 NACRES: NA.25 General descriptionLysophosphotidylethanolamine (LPE) is a phospholipid that belongs to a group called as cephalins. It is a membrane glycerolipid.ApplicationBrain Lyso PE has been used as a calibrant in ion mobility-mass spectrometry (IM-MS). It has also been used as a calibrant in hydrophilic interaction chromatography.Packaging5 mL Amber Glass Screw Cap Vial (850095P-10mg)Параметрыassay >99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC) form powder packaging pkg of 1 x 10 mg (850095P-10mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string CCCCCCCCCCCCCCCC/C=C\OC[C@](O)([H])COP([O-])(OCC[NH3+])=O
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Brain Lyso PS
CAS Number: 383907-66-2 NACRES: NA.25
Кат. номер 850092P-5MG 850092P-10MG General descriptionLyso-phosphatidylserine (lyso-PS) is produced by the enzymatic action of phospholipase A1 and A2 on phosphatidylserine.ApplicationBrain Lyso PS is suitable for use:- as standard to quantify lipids using ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS)
- in the preparation of liposomes for coating dynabeads for binding of factor H (fH)
- as a ligand for G-protein coupled receptor 34 (GPR34) in in vitro experiments to investigate its effect granulosa cells(GC) and hormone production
- as substrate for sicariid phospholipase D (PLD) toxins (SicTox) enzymes
Biochem/physiol ActionsLyso-Phosphatidylserine (Lyso-PS) plays a key role in histamine release from mast cells. Lyso-PS inhibits the growth to T cells. It is a chemotactic substance for fibroblast and tumor cells. Lyso-PS is involved in tumor progression and allergic reactions.Packaging5 mL Amber Glass Screw Cap Vial (850092P-5mg)
5 mL Amber Glass Screw Cap Vial (850092P-10mg)Параметрыassay >99% (LPS; may contain up to 10% of the 2-LPS isomer, TLC) form powder packaging pkg of 1 x 10 mg (850092P-10mg), pkg of 1 x 5 mg (850092P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string O[C@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]
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Brain PC
CAS Number: 383907-52-6 NACRES: NA.25
Кат. номер 840053C-25MG 840053C-200MG General descriptionPhosphatidylcholine (PC) is a predominant glycerophospholipid in eukaryotes. Brain PC predominantly contains PC 16:0/16:0 and PC 16:0/18:1.ApplicationBrain PC is suitable for use in the preparation of lipid mixture for microplate (enzyme linked immunosorbent assay (ELISA))-based recognition of glycolipid-protein interaction assay and liposomes for co-sedimentation assay. Brain PC has been used in the preparation of liposomes for integration of receptors.Biochem/physiol ActionsPhosphatidylcholine (PC) is the major source of second messengers and lipid mediators. It is intermediate in the synthesis of other phospholipids.Packaging5 mL Clear Glass Sealed Ampule (840053C-200mg)
5 mL Clear Glass Sealed Ampule (840053C-25mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (840053C-25mg), pkg of 2 x 4 mL (840053C-200mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (840053C-25mg), 25 mg/mL (840053C-200mg) shipped in dry ice storage temp. −20°C SMILES string [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
Brain PE
CAS Number: 383907-18-4 NACRES: NA.25
Кат. номер 840022C-25MG 840022C-200MG General descriptionContains ~50% plasmalogen ether lipidApplicationBrain PE has been used as a cofactor to support the replication of highly infectious prion protein (PrPSc). It has also been used for the preparation of liposomes.Packaging5 mL Clear Glass Sealed Ampule (840022C-200mg)
5 mL Clear Glass Sealed Ampule (840022C-25mg)Параметрыassay >99% (TLC) packaging pkg of 1 x 2.5 mL (840022C-25mg), pkg of 2 x 4 mL (840022C-200mg) Торговая марка Avanti Polar Lipids concentration 10 mg/mL (840022C-25mg), 25 mg/mL (840022C-200mg) shipped in dry ice storage temp. −20°C SMILES string [H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O
Safety Informationpictograms GHS06,GHS08 signalword Danger hcodes H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 pcodes P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 Target Organs Central nervous system RIDADR UN 1888 6.1 / PGIII WGK Germany WGK 3 Flash Point F does not flash Flash Point C does not flash Узнать цену -
Brain PI(4)P
CAS Number: 475995-51-8 NACRES: NA.25
Кат. номер 840045P-10MG 840045P-5MG 840045P-25MG 840045P-1MG General descriptionPhosphatidylinositol 4-phosphate (PI4P) acts as a precursor of phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P2]. It is found in the membranes of Golgi apparatus.Packaging5 mL Clear Glass Sealed Ampule (840045P-5mg)
5 mL Clear Glass Sealed Ampule (840045P-1mg)
5 mL Clear Glass Sealed Ampule (840045P-10mg)
5 mL Clear Glass Sealed Ampule (840045P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (840045P-1mg), pkg of 1 x 10 mg (840045P-10mg), pkg of 1 x 25 mg (840045P-25mg), pkg of 1 x 5 mg (840045P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]
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Brain PI(4,5)P2
CAS Number: 383907-42-4
Кат. номер 840046P-10MG 840046P-5MG 840046P-25MG 840046P-1MG General descriptionPhosphatidylinositol 4,5-bisphosphate (PIP2) is synthesized from the precursor phosphatidylinositol 4-phosphate(PI4P). PIP2 is a phosphoinositide with three negative charges.
Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.ApplicationBrain PI(4,5)P2 has been used:- in the preparation of Folch liposome
- in the preparation of giant unilamellar vesicles and multilamellar lipid sheets
- as a substrate for rubidium flux assay
- in the biochemical reaction assay mixture for various lipid kinases like Phosphatidylinositol-3-kinase gamma (PI3K), Phosphatidylinositol-3-kinase beta (PI3K), Phosphatidylinositol-3-kinase gamma (PI3K)
Biochem/physiol ActionsPhosphatidylinositol 4,5-bisphosphate (PIP2) is a signaling phospholipid, present in the plasma membrane. It acts as a precursor for inositide 3 phosphate, diacylglycerol. PIP2 is a gating ligand for most of the ion channels. It functions as an activatory ligand for eukaryotic inward rectifier potassium (Kir) channels.Packaging5 mL Clear Glass Sealed Ampule (840046P-5mg)
5 mL Clear Glass Sealed Ampule (840046P-1mg)
5 mL Clear Glass Sealed Ampule (840046P-10mg)
5 mL Clear Glass Sealed Ampule (840046P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 mg (840046P-1mg), pkg of 1 x 10 mg (840046P-10mg), pkg of 1 x 25 mg (840046P-25mg), pkg of 1 x 5 mg (840046P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@H]1O)([O-])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
Brain PS
CAS Number: 383907-32-2 NACRES: NA.25
Кат. номер 840032P-100MG 840032P-500MG 840032P-25MG 840032P-10MG ApplicationBrain PS has been used in lipid standard material preparation, reporter assay and in the preparation of liposomes.Biochem/physiol ActionsPhosphatidylserine is a lipid. It helps to increase the cognitive performance of rats and humans, having different levels of age-dependent memory problems or probable Alzheimer disease. It has the ability to block degeneration of the cholinergic neuronal population of the basal forebrain of aged rats. 90% of the phosphatidylserine decarboxylase activity is linked with mitochondria.Packaging5 mL Clear Glass Sealed Ampule (840032P-100mg)
5 mL Clear Glass Sealed Ampule (840032P-500mg)
5 mL Clear Glass Sealed Ampule (840032P-10mg)
5 mL Clear Glass Sealed Ampule (840032P-25mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 10 mg (840032P-10mg), pkg of 1 x 100 mg (840032P-100mg), pkg of 5 x 100 mg (840032P-500mg), pkg of 1 x 25 mg (840032P-25mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]
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Brain SM
CAS Number: 383907-91-3 NACRES: NA.25
Кат. номер 860062P-200MG 860062P-500MG 860062P-1G 860062P-25MG General descriptionAs a major constituent of cell membranes, sphingomyelin is found at particularly high concentrations in the membranes of nerve cells (in the myelin sheaths) and red blood cells. It was previously thought to have a purely structural role, similar to the function of phosphatidylcholine, through intermolecular interactions mediated by the 2-amide group, the 3-hydroxy group and the 4,5-trans double bond of the sphingoid base. However, it is now appreciated that sphingomyelin has a high affinity for cholesterol and that these two lipids pack tightly into liquid-ordered domains among a liquid-disordered phase to form lipid rafts. These membrane microdomains are thought to function as signaling platforms that regulate the localization and interactions of proteins. But sphingomyelin does not just influence signaling as a component of lipid rafts — it is also a precursor to ceramides and other sphingolipid metabolites that comprise the sphingomyelin cycle or sphingolipid network.
Sphingomyelin and related lipids,ApplicationBrain SM is suitable:- as a standard for high-performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS)
- as a supplement for cell vacuolation of Hela cells
- for preparation of liposomes
Packaging5 mL Amber Glass Screw Cap Vial (860062P-25mg)
20 mL Clear Glass Screw Cap Vial (860062P-500mg)
5 mL Amber Glass Screw Cap Vial (860062P-200mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (860062P-1g)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 1 g (860062P-1g), pkg of 1 x 200 mg (860062P-200mg), pkg of 1 x 25 mg (860062P-25mg), pkg of 1 x 500 mg (860062P-500mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O
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Brain Sphingosine 860025P-5MG
CAS Number: 477243-03-1 General descriptionBrain sphingosine is a central metabolite, which is produced from the de novo synthesis of cellular sphingolipids. It is involved in growth, differentiation, survival and cell death. D-erythro-Sphingosine acts as a pharmacological inhibitor of protein kinase C in human platelets. It prevents platelet aggregation in cells.ApplicationBrain sphingosine has been used as a standard in the fluorimetric determination of sphingosine in porcine enterocyte monosialogangliosides.Packaging5 mL Amber Glass Screw Cap Vial (860025P-5mg)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (860025P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
Brassicasterol 700175P-5MG
Empirical Formula (Hill Notation): C28H46O CAS Number: 474-67-9 Molecular Weight: 398.66 NACRES: NA.25 General descriptionBrassicasterol is a plant sterol, sharing similar structure with cholesterol. It is obtained through the dietary sources, including sea food.Biochem/physiol ActionsBrassica sterol in cerebrospinal fluid might serve as an indicator for Alzheimer′s disease. It is found in rapeseed oil. Brassicasterol is thus, useful in identifying brassica oil and contamination of rapeseed and canola oil in others. Plant sterols can penetrate through the blood brain barrier.Packaging5 mL Amber Glass Screw Cap Vial (700175P-5MG)Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 5 mg (700175P-5MG) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string CC1(CC[C@H](O)C2)C2=CCC3C1CCC4(C)C3CCC4C(/C=C/[C@H](C)C(C)C)C InChI 1S/C28H46O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-9,18-20,22-26,29H,10-17H2,1-6H3/b8-7+/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1 InChI key OILXMJHPFNGGTO-ZAUYPBDWSA-N
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
C10 bisphosphonate 860480P-500UG
Empirical Formula (Hill Notation): C10H25NO6P2 CAS Number: 15049-93-1 Molecular Weight: 317.26 NACRES: NA.25 ApplicationC10 bisphosphonate is suitable for use as an inhibitor for acid sphingomyelinase.Biochem/physiol ActionsC10 bisphosphonate, with prolonged carbon chain, is an inhibitor for acid sphingomyelinase and may be a treatment option for inflammatory lung diseases, cystic fibrosis and atherosclerosis. It interacts with the divalent metal ions and forms bidentate complexes. Bisphosphonates are inhibitors of end reaction in pathways. It is an inhibitor of cytosolic farnesyl diphosphate (FDP) synthase (geranyl diphosphate (GDP) and geranylgeranyl diphosphate (GGDP) synthase and isoprene pathway. Bisphosphonates have antimicrobial functionality and inhibits the growth of Entamoeba histolytica and Plasmodium falciparum.Packaging5 mL Amber Glass Screw Cap Vial (860480P-500ug)Параметрыform powder packaging pkg of 1 x 500 μg (860480P-500ug) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. −20°C SMILES string [NH3+]C(P([O-])(O)=O)(P(O)(O)=O)CCCCCCCCC
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену -
C10 Ceramide (d18:1/10:0) 860510P-5MG
Empirical Formula (Hill Notation): C28H55NO3 CAS Number: 111122-57-7 Molecular Weight: 453.74 NACRES: NA.25 General descriptionC10 Ceramide (d18:1/10:0) is a synthetic ceramide containing sphingosine with decanoic acid. It has a short acyl chain length than sphingosine acyl chain.ApplicationC10 Ceramide (d18:1/10:0) or N-decanoyl-D-erythro-sphingosine has been used:- as an internal standard in galactocerebrosidase (GALC) assay
- to study its role on the physical properties of edible organogels and on their ability to induce cell death of various cancer cell lines
- to study its mixing behavior with other ceramides having the same sphingosine base but varying N-linked acyl chain length
Biochem/physiol ActionsCeramides modulate stress responses and inflammation. It also controls cell differentiation, proliferation and apoptosis.Packaging5 mL Amber Glass Screw Cap Vial (860510P-5mg)Параметрыform powder packaging pkg of 1 x 5 mg (860510P-5mg) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C SMILES string OC[C@]([H])(NC(CCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
C11 TopFluor® Ceramide 810262P-250UG
Empirical Formula (Hill Notation): C42H70N3O3F2 CAS Number: 1246355-58-7 Molecular Weight: 703.02 NACRES: NA.25 General descriptionCeramide, a bioactive sphingolipid belongs to the sphingolipid family of cell lipids. This pore-forming member is insoluble in water. It is a hygroscopic and light sensitive lipid.ApplicationC11 TopFluor® Ceramide may be used:- in the ceramide and B-cell lymphoma-extra-large (Bcl-xL) binding studies to study the effect on ceramide channel formation
- as a tracer in confocal microscopy to treat T84 cells in order to study its localization in sphingomyelinase (SMase)-induced F-actin structures
- to study its effect on the migration of pancreatic cancer stem cells (PCSC) using confocal microscopy
Biochem/physiol ActionsCeramide is known to participate in apoptosis, mediated by mitochondria. Ceramide channels plays a key role in the onset of apoptosis in vivo.Packaging5 mL Amber Glass Screw Cap Vial (810262P-250ug)Legal InformationTopFluor is a registered trademark of Avanti Polar Lipids, Inc.Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 250 µg (810262P-250ug) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport Узнать цену -
C11 TopFluor® Ceramide-1-Phosphate 810270P-250UG
Empirical Formula (Hill Notation): C42H74BF2N4O6P CAS Number: 2260795-50-2 Molecular Weight: 810.84 NACRES: NA.25 General descriptionCeramide-1-phosphate (C1P), an anti-apoptotic lipid is produced with the help of ceramide kinase (CERK) by the direct phosphorylation of ceramide.
The availability of this new fluorescent metabolite provides the researcher with new ways to track cell migration and G protein coupled activity.ApplicationC11 TopFluor® Ceramide-1-Phosphate may be used to study its effect on the migration of pancreatic cancer stem cells (PCSC) using confocal microscopy.Biochem/physiol ActionsCeramide-1-phosphate (C1P) is capable of blocking cell death in bone marrow-derived macrophages (BMDMs). It controls the growth and survival in various cell types. C1P bioactive sphingolipid is known to modulate the proliferation and differentiation of photoreceptors. C1P controls apoptosis. It acts as a pro-inflammatory agent and plays a key role in phagocytosis. Ceramide-1-phosphate is well known as a second messenger and an important mediator of inflammatory response.Packaging5 mL Amber Glass Screw Cap Vial (810270P-250ug)Legal InformationTopFluor is a registered trademark of Avanti Polar Lipids, Inc.Параметрыassay >99% (TLC) form powder packaging pkg of 1 x 250 µg (810270P-250ug) Торговая марка Avanti Polar Lipids shipped in dry ice storage temp. 20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Узнать цену
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С 2010 года мы поставляем оборудование с заводов Европы. Берем на себя все — от подбора оборудования до внедрения на предприятии
Все сотрудники имеют высшее образование, закончили ведущие химические вузы страны, такие как РХТУ им Менделеева.
У большинства компаний срок ожидания составляет 10-12 недель.
Оборудование хранится на сухом отапливаемом складе, где поддерживается ровная температура.
Работаем с PonyExpress и Деловыми линиями. Вы также можете выбрать свою транспортную компанию или забрать товар со склада в Москве.
В случае любых неполадок за свой счет выполним ремонт в сервисном центре или на заводе-изготовителе. Или бесплатно заменим прибор на новый.
Производим пуско-наладку оборудования, валидацию, обучение сотрудников. Если нужно, привлекаем инженеров с заводов- изготовителей.
