Cell Culture &amp; Analysis

Porcine Serum has been used:

in the neutralization of lipofectamine coated adeno-associated viruses (AAVs)
for inducing liver fibrosis in rats
as a standard negative reference in enzyme-linked immunosorbent assay (ELISA)
as a component of trypticase soy broth with 0.6% yeast extract (TSBYE) for culturing A. actinomycetemcomitans strains

Pig serum acute phase proteins (APP) show elevation with age. It is used for the culture of porcine islet cells.

Collected from adult animals.

Quality Level	500
biological source	Porcine
sterility	sterile-filtered
composition	hemoglobin, ≤50 mg/dL
origin	USA origin
application(s)	cell culture \| mammalian: suitable
impurities	≤20 EU/mL endotoxin
shipped in	dry ice
storage temp.	−20°C

Rabbit serum is used to support cultures of Borrelia burgdorferi, the causative agent of Lyme disease.
Rabbit Serum is used for the following applications:

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Rabbit Serum

MDL number:	MFCD00164118
NACRES:	NA.71

sampling for bacteriological cultures and culture conditions
as a supplement in BSK-S medium in a study to evaluate the infectivity and pathogenicity of BL206 and B515 grown in BSK medium containing this product vs the medium containing Sigma rabbit serum R7136
light microscopy, immunocytochemistry and immunohistochemistry.
immunoelectron microscopy

biological source	rabbit
Quality Level	500
sterility	sterile-filtered
quality	USDA approved
composition	hemoglobin (tested)
origin	USA origin
application(s)	cell culture \| mammalian: suitable
impurities	endotoxin, tested, mycoplasma, tested
shipped in	dry ice
storage temp.	20°C

Mouse serum is used in a variety of mouse cell culture systems to study viral infection, inhibition and transduction processes.

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Sera from mouse

Suitability

Not tested for use in cell culture

Quality Level	300
biological source	mouse
description	Contains no azides
sterility	sterile; aseptically filled
form	frozen liquid (from clotted whole blood)
origin	USA origin
shipped in	dry ice
storage temp.	−20°C

Sheep serum is useful for the propagation of long-term cultures of erythrocytic stages of the Theileria uilenbergi intracellular protozoan parasite.

Personal Protective Equipment	Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Sheep Serum

Collected from adult animals.

Quality Level	500
biological source	sheep
sterility	sterile-filtered
composition	hemoglobin, ≤50 mg/dL
origin	USA origin
application(s)	cell culture \| mammalian: suitable
impurities	≤100 EU/mL endotoxin
shipped in	dry ice
storage temp.	−20°C

Jasmonic acid (JA) is a plant hormone derived from linolenic acid. Jasmonic acid is involved in plant cell signaling responses to abiotic and biotic stress. JA is involved in the regulation of processes that include growth inhibition, senescence, flower development, leaf abscission and tendril coiling. JA is also involved in wound healing of plants and systemic acquired resistance to attack by insects.

Personal Protective Equipment	Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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(±)-Jasmonic acid

Empirical Formula (Hill Notation):	C₁₂H₁₈O₃
CAS Number:	77026-92-7
Molecular Weight:	210.27
MDL number:	MFCD04221274
PubChem Substance ID:	24896192
NACRES:	NA.72

100 mg in serum bottle

Note: This product is a clear, colorless to very light yellow oil that adheres to the surface of the vial.

Quality Level	200
product line	BioReagent
form	liquid
application(s)	cell culture \| plant: suitable
Featured Industry	Agriculture
storage temp.	2-8°C
SMILES string	CC\C=C/C[C@H]1[C@@H](CCC1=O)CC(O)=O
InChI	1S/C12H18O3/c1-2-3-4-5-10-9(8-12(14)15)6-7-11(10)13/h3-4,9-10H,2,5-8H2,1H3,(H,14,15)/b4-3-/t9-,10-/m0/s1
InChI key	ZNJFBWYDHIGLCU-CMIOBCHKSA-N

1-Naphthaleneacetic acid (NAA) is a synthetic phytohormone auxin that is added to cell culture media such as Murashige & Skoog media and Chus N6 media.
1-Naphthaleneacetic acid has been used:

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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1-Naphthaleneacetic acid

Empirical Formula (Hill Notation):	C₁₂H₁₀O₂
CAS Number:	86-87-3
Molecular Weight:	186.21
Beilstein/REAXYS Number:	1308415
EC Number:	201-705-8
MDL number:	MFCD00004046
PubChem Substance ID:	24897435
NACRES:	NA.72

to modify MS media for the initiation of callus
as a supplement in solid K3 medium for the selection of transformants
in the preparation of culture medium like V-KM medium and Cg medium

25, 100 g in poly bottle

1-Naphthaleneacetic acid is one of the synthetic auxins, used in plant propagation. It can induce the formation of lateral and adventitious roots.

Quality Level	200
product line	BioReagent
assay	≥95%
form	crystalline
application(s)	cell culture \| plant: suitable
color	white to light yellow
Featured Industry	Agriculture
SMILES string	OC(=O)Cc1cccc2ccccc12
InChI	1S/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)
InChI key	PRPINYUDVPFIRX-UHFFFAOYSA-N
Gene Information	human ... CCKAR(886), CCKBR(887)

3-Indoleacetic acid has been used:

Pictograms	GHS05,GHS07
Signal Word	Danger
Hazard Statements	H302 - H315 - H318 - H335 - H412
Precautionary Statements	P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Target Organs	Respiratory system
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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3-Indoleacetic acid

Empirical Formula (Hill Notation):	C₁₀H₉NO₂
CAS Number:	87-51-4
Molecular Weight:	175.18
Beilstein/REAXYS Number:	143358
EC Number:	201-748-2
MDL number:	MFCD00005636
PubChem Substance ID:	24896015
NACRES:	NA.72

as standard to quantify hormones
to modify MS (Murashige and Skoog) media for the initiation of callus
as an external standard in the analyses of free endogenous growth regulators

Indole-3-acetic acid (IAA) is a natural phytohormone (plant auxin) used as a supplement in media such as Murashige and Skoog media and Gamborgs B5 media. IAA is a plant signaling molecule involved in plant organogenesis and growth control.

5, 25, 100 g in poly bottle

Quality Level	200
assay	≥98%
form	crystalline
application(s)	cell culture \| plant: suitable
color	white to pink
mp	165-169 °C (lit.)
Featured Industry	Agriculture
storage temp.	−20°C
SMILES string	OC(=O)Cc1c[nH]c2ccccc12
InChI	1S/C10H9NO2/c12-10(13)5-7-6-11-9-4-2-1-3-8(7)9/h1-4,6,11H,5H2,(H,12,13)
InChI key	SEOVTRFCIGRIMH-UHFFFAOYSA-N

6-Benzylaminopurine, benzyl adenine (BAP) is a synthetic cytokinin.

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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6-Benzylaminopurine solution B3274-50ML

MDL number:	MFCD00005572
PubChem Substance ID:	24891695
NACRES:	NA.72

General description

6-Benzylaminopurine solution has been used as a component in the Murashige & Skoog medium (MS) for culturing mandarin explants and plantlets of Dendrocalamus asper (Schultes f.). It has also been used as a supplement in Nitsch and Nitsch medium (NN) of grapevine explants,

6-Benzylaminopurine (BAP) is used as a cytokinin supplement to plant growth medium It increases post-harvest life of green vegetables by preventing chlorophyll degradation. It is used in micropropagation. However, in some plants, BAP leads to inhibition in growth and root formation. BAP phenyl ring based derivatives are widely used to test their anti-cancer effects

Quality Level	200
sterility	sterile-filtered
concentration	1 mg/mL
application(s)	cell culture \| plant: suitable
Featured Industry	Agriculture
storage temp.	2-8°C
SMILES string	C(Nc1ncnc2nc[nH]c12)c3ccccc3
InChI	1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)
InChI key	NWBJYWHLCVSVIJ-UHFFFAOYSA-N

Alginic acid, alginate, is an anionic polysaccharide distributed widely in the cell walls of brown algae. Alginate is biocompatible and gels in the presence of divalent cations such as calcium making it useful for cell encapsulation and immobilization. Immobilized cells have use in bioproduction and bioremediation processes.

Personal Protective Equipment	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Abscisic Acid Immunoassay Detection Kit

NACRES: NA.84

Кат. номер

PGR1-1KT-PW

PGR1-1KT

Application
Abscisic Acid Immunoassay Detection Kit is used to quantitate the levels of abscisic acid (ABA) throughtout plant tissues under normal and stress conditions.
Параметры

Quality Level 100,

Featured Industry Agriculture

storage temp. 2-8°C

Safety Information

RIDADR NONH for all modes of transport

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Alginic acid sodium salt from brown algae

CAS Number:	9005-38-3
MDL number:	MFCD00081310
NACRES:	NA.72

100 g in poly bottle

A straight-chain, hydrophilic, colloidal, polyuronic acid composed of glucuronic and mannuronic acid residues.

Quality Level	200
biological source	algae (brown)
product line	BioReagent
form	powder
application(s)	cell culture \| plant: suitable
viscosity	4-12 cP, 1 % in H₂O(25 °C)(lit.)
Featured Industry	Agriculture

Chemical structure: -lactam

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Cefotaxime sodium salt

Empirical Formula (Hill Notation):	C₁₆H₁₆N₅NaO₇S₂
CAS Number:	64485-93-4
Molecular Weight:	477.45
Beilstein/REAXYS Number:	5711411
EC Number:	264-915-9
MDL number:	MFCD00079073
PubChem Substance ID:	24892923
NACRES:	NA.72

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.

Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Broad spectrum third generation cephalosporin antibiotic.
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

Quality Level	200
product line	BioReagent
form	powder
application(s)	cell culture \| plant: suitable
color	white to light yellow
solubility	H₂O: soluble (aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.)
Featured Industry	Agriculture
Mode of action	cell wall synthesis \| interferes
antibiotic activity spectrum	Gram-negative bacteria, Gram-positive bacteria
storage temp.	2-8°C
SMILES string	[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O
InChI	1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
InChI key	AZZMGZXNTDTSME-JUZDKLSSSA-M

Colchicine is a tricyclic alkaloid that can stay in circulation for 20 to 40 hours post intake. Leucocytes harbour maximum colchicine. It contains three hexameric rings termed A, B and C.

Pictograms	GHS08
Signal Word	Danger
Hazard Statements	H317 - H334
Precautionary Statements	P261 - P280 - P342 + P311
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Colchicine

Empirical Formula (Hill Notation):	C₂₂H₂₅NO₆
CAS Number:	64-86-8
Molecular Weight:	399.44
Beilstein/REAXYS Number:	2228813
EC Number:	200-598-5
MDL number:	MFCD00078484
PubChem Substance ID:	24892656
NACRES:	NA.72

Colchicine has been used:

as an inhibitor of tubulin polymerization in bone-marrow-derived macrophages
for the inhibition of in vitro neurite outgrowth in human neuronal cells
as microtubule destabilizer to induce peripheral neuropathy in induced pluripotent stem cell derived neurons (iPSC-Neurons)

1, 5 g in glass bottle
500 mg in glass bottle

Colchicine interacts with albumin and binds to tubulin. Its association with tubulin impacts autophagic vacuole fusion with lysosomes. It inhibits tyrosine kinases and phospholipases. Colchicine may be useful for treating acute coronary syndromes. It is prescribed for treating rheumatologic conditions including familial mediterranean fever (FMF) and acute gouty arthritis.
Colchicine is an inhibitor of microtubule polymerization which blocks chromosome segregation during meiosis. Consequently, Colchicine is used to induce polyploidy (tetraploid) in plant cells.

Quality Level	200
product line	BioReagent
assay	95% (HPLC)
application(s)	cell culture \| plant: suitable
mp	150-160 °C (dec.) (lit.)
Featured Industry	Agriculture
SMILES string	COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(OC)c(OC)c(OC)c23)NC(C)=O
InChI	1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
InChI key	IAKHMKGGTNLKSZ-INIZCTEOSA-N
Gene Information	human ... ABCB1(5243), CYP3A4(1576), TUBA1A(7846), TUBA1B(10376), TUBA1C(84790), TUBA3C(7278), TUBA3E(112714), TUBA4A(7277), TUBB(203068), TUBB1(81027), TUBB2A(7280), TUBB2B(347733), TUBB3(10381), TUBB4A(10382), TUBB4B(10383), TUBB6(84617), TUBB8(347688) mouse ... Abcb1a(18671), Abcb1b(18669)

Gibberellic acid is a tetracyclic diterpenoid compound, which is synthesized by terpenoid pathway in chloroplasts, cytoplasm, plastid, and endoplasmic reticulum.
Gibberellic acid is an endogenous plant growth regulator

Pictograms	GHS06,GHS08
Signal Word	Danger
Hazard Statements	H300 - H340
Precautionary Statements	P202 - P264 - P270 - P280 - P301 + P310 - P405
Personal Protective Equipment	Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RIDADR	UN 1544PSN1 6.1 / PGI
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Gibberellic acid

Empirical Formula (Hill Notation):	C₁₉H₂₂O₆
CAS Number:	77-06-5
Molecular Weight:	346.37
Beilstein/REAXYS Number:	54346
EC Number:	201-001-0
MDL number:	MFCD00079329
PubChem Substance ID:	24895317
NACRES:	NA.72

Gibberellic acid has been used as a supplement in Murashige and Skoog media (MS) for treating young leaves of hybrid poplar to follow MYB transcription factor PtrMYB012 expression and in vitro peas seed germination. It has also been used in gibberellic acid (GA)-sensitivity assay in wheat seeds and to promote seed germination in Arabidopsis seeds.
The specific actions of Gibberellin A3 (G1025, G7645) and A4 (G7276) or combinations of Gibberellins should be determined in specific plant applications.

1 g in glass bottle

Phytohormone that controls important aspects of plant growth: germination, elongation, and flowering. The effects are mediated by inducing degradation of the DELLA repressor protein, and probably other minor signalling pathways.
Gibberellic acids (GA) are important plant growth hormones that promote plant cell growth and elongation. Gibberellins promote rapid stem and root growth, induce mitotic division and initiate (break dormancy) and increase seed germination rates. The gibberellins are also involved in processes such as gravitropism and flowering.

Quality Level	200
product line	BioReagent
assay	90% gibberellin A₃ basis (of total gibberellins.)
application(s)	cell culture \| plant: suitable
Featured Industry	Agriculture
SMILES string	C[C@]12[C@@H](O)C=C[C@@]3(OC1=O)[C@@H]4CC[C@]5(O)C[C@]4(CC5=C)[C@H]([C@H]23)C(O)=O
InChI	1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10-,11+,12-,13-,16-,17+,18+,19-/m1/s1
InChI key	IXORZMNAPKEEDV-OBDJNFEBSA-N

Indole-3-butyric acid (IBA) is auxin-family plant hormone (phytohormone). IBA is thought to be a precursor of indole-3-acetic acid (IAA) the most abundant and the basic auxin natively occurring and functioning in plants. IAA generates the majority of auxin effects in intact plants, and is the most potent native auxin.

Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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G0154-500ML

Guillards (F/2) Marine Water Enrichment Solution G0154-500ML

NACRES: NA.72

Application
Guillards (F/2) Marine Water Enrichment Solution 50 X, is a concentrate of major nutrients, trace metals and vitamins that can be diluted in filtered seawater to support reconstitution of Guillards (F/2) Marine Enrichment medium. Guillards (F/2) Marine Enrichment medium is a widely used enriched seawater medium for growing costal marine algae (diatoms).
Formula variant
Without silicate. With the major nutrients, trace metals and vitamins as described by Guillard (1975).
Reconstitution
Use at 20ml/L of seawater.

Phycology Media composition and preparation from powder
Параметры

sterility sterile-filtered

Quality Level 400

form liquid

concentration 50 x

application(s) cell culture | plant: suitable

Featured Industry Agriculture

shipped in dry ice

storage temp. −20°C

Safety Information

RIDADR NONH for all modes of transport

WGK Germany WGK 1

Flash Point(F) Not applicable

Flash Point(C) Not applicable

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Indole-3-butyric acid

Empirical Formula (Hill Notation):	C₁₂H₁₃NO₂
CAS Number:	133-32-4
Molecular Weight:	203.24
Beilstein/REAXYS Number:	171120
EC Number:	205-101-5
MDL number:	MFCD00005664
PubChem Substance ID:	24896067

1, 5, 25 g in poly bottle

Quality Level	200
product line	BioReagent
application(s)	cell culture \| plant: suitable
Featured Industry	Agriculture
storage temp.	2-8°C
SMILES string	OC(=O)CCCc1c[nH]c2ccccc12
InChI	1S/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)
InChI key	JTEDVYBZBROSJT-UHFFFAOYSA-N

Kinetin is a cell division factor or cytokinin from DNA. It occurs naturally in various plant extracts such as those from coconuts, maize endosperm, banana and horsechestnut fruits, carrot and tobacco leaves, grapes, crown gall tumors, female gametophytes of Ginkgo and many other sources.

Pictograms	GHS06
Signal Word	Danger
Hazard Statements	H301
Precautionary Statements	P264 - P270 - P301 + P310 - P405 - P501
Personal Protective Equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Kinetin

Empirical Formula (Hill Notation):	C₁₀H₉N₅O
CAS Number:	525-79-1
Molecular Weight:	215.21
Beilstein/REAXYS Number:	21703
EC Number:	208-382-2
MDL number:	MFCD00075757
PubChem Substance ID:	24896230
NACRES:	NA.72

Kinetin has been used as a supplement in modified MS medium for culturing various plant tissues. It has also been used to study its effect on thymus and immune function of aging rats.

5, 25 g in glass bottle
1 g in poly bottle

Kinetin has an ability to induce cell division differentiation and growth. In addition, it also acts as an antioxidant and delays the aging process. Kinetin acts as a potential tool for studying effects of red light on plants.
Kinetin is an adenine-type cytokinin phytohormone that is used in plant culture media such as Murashige & Skoog media in conjunction with auxins such as indole-3-acetic acid (IAA), Indole-3-butyric acid (IBA), 1-napthaleneacetic acid (NAA) or others to induce the fomation of callus and to regenerate plant tissues from callus.

Quality Level	200
product line	BioReagent
assay	98% (TLC and HPLC)
form	amorphous powder
application(s)	cell culture \| plant: suitable
color	off-white
mp	264-270 °C (dec.) (lit.)
Featured Industry	Agriculture
SMILES string	C(Nc1ncnc2[nH]cnc12)c3ccco3
InChI	1S/C10H9N5O/c1-2-7(16-3-1)4-11-9-8-10(13-5-12-8)15-6-14-9/h1-3,5-6H,4H2,(H2,11,12,13,14,15)
InChI key	QANMHLXAZMSUEX-UHFFFAOYSA-N

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Kinetin riboside

Empirical Formula (Hill Notation):	C₁₅H₁₇N₅O₅
CAS Number:	4338-47-0
Molecular Weight:	347.33
EC Number:	224-389-3
MDL number:	MFCD00037987
PubChem Substance ID:	24896224
NACRES:	NA.72

5, 100 g in glass bottle

Kinetin riboside, a cytokinin riboside plant hormone with anticancer activity, has been used to study differentiation and apoptosis processes in myeloid leukemia cells, plant tumor cells (crown-gall) and other cancers.

Quality Level	300,
assay	98% (HPLC), 98% (TLC)
form	powder
solubility	acetic acid: 49.00-51.00 mg/mL, clear, colorless to yellow
storage temp.	2-8°C
SMILES string	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccco4)ncnc23
InChI	1S/C15H17N5O5/c21-5-9-11(22)12(23)15(25-9)20-7-19-10-13(17-6-18-14(10)20)16-4-8-2-1-3-24-8/h1-3,6-7,9,11-12,15,21-23H,4-5H2,(H,16,17,18)/t9-,11-,12-,15-/m1/s1
InChI key	CAGLGYNQQSIUGX-SDBHATRESA-N
Gene Information	rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

N-(2-Chloro-4-pyridyl)-N-phenylurea has been used as a supplement in Murashige and Tucker medium (MT) to culture thin cell layer (TCL) explants. It has also been used to spray on to the ovaries at anthesis for induction of parthenocarpic fruit.
Forchlorfenuron (CPPU) is a cytokinin that enhances in vitro direct shoot organogenesis of Citrus aurantium L. epicotyl segments.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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N-(2-Chloro-4-pyridyl)-N-phenylurea

Empirical Formula (Hill Notation):	C₁₂H₁₀ClN₃O
CAS Number:	68157-60-8
Molecular Weight:	247.68
MDL number:	MFCD00059898
PubChem Substance ID:	24892531
NACRES:	NA.72

25 mg in poly bottle

CPPU is a cytokinin oxidase/dehydrogenase (CKO) inhibitor.
N-(2-Chloro-4-pyridyl)-N-phenylurea/ CPPU, a cytokinin-like plant growth regulator participates in chlorophyll biosynthesis, cell division and cell expansion. It helps to intensify fruit set and quickens fruit enlargement. CPPU modulates carbohydrate allocation.

Quality Level	200,
product line	BioReagent
Featured Industry	Agriculture
storage temp.	2-8°C
SMILES string	Clc1cc(NC(=O)Nc2ccccc2)ccn1
InChI	1S/C12H10ClN3O/c13-11-8-10(6-7-14-11)16-12(17)15-9-4-2-1-3-5-9/h1-8H,(H2,14,15,16,17)
InChI key	GPXLRLUVLMHHIK-UHFFFAOYSA-N

Thidiazuron (TDZ) is a plant growth regulator used in micropropagations to supplement media such as Murashige and Skoog medium. TDZ promotes plant organogenesis (shoot regeneration) and plant regeneration. Thidiazuron (TDZ) enables the production of virus-free stock plants, speeds up breeding, and provides new genotypes for the market.

pictograms	GHS08,GHS09
signalword	Warning
hcodes	H351 - H411
pcodes	P273 - P281
Personal Protective Equipment	dust mask type N95 (US),, Eyeshields,, Gloves,
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Thidiazuron

Empirical Formula (Hill Notation):	C₉H₈N₄OS
CAS Number:	51707-55-2
Molecular Weight:	220.25
Beilstein/REAXYS Number:	1078092
EC Number:	257-356-7
MDL number:	MFCD00078723
PubChem Substance ID:	24898652
NACRES:	NA.72

500 mg in poly bottle
Bottomless glass bottle. Contents are inside inserted fused cone.

Quality Level	200
product line	BioReagent
application(s)	cell culture \| plant: suitable
Featured Industry	Agriculture
SMILES string	O=C(Nc1ccccc1)Nc2cnns2
InChI	1S/C9H8N4OS/c14-9(12-8-6-10-13-15-8)11-7-4-2-1-3-5-7/h1-6H,(H2,11,12,14)
InChI key	HFCYZXMHUIHAQI-UHFFFAOYSA-N

trans-Zeatin contains a hydroxylated isoprenoid side chain.

Pictograms	GHS07,GHS09
Signal Word	Warning
Hazard Statements	H315 - H319 - H335 - H410
Precautionary Statements	P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
Target Organs	Respiratory system
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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trans-Zeatin

Empirical Formula (Hill Notation):	C₁₀H₁₃N₅O
CAS Number:	1637-39-4
Molecular Weight:	219.24
Beilstein/REAXYS Number:	616241
MDL number:	MFCD00213654
PubChem Substance ID:	24902170
NACRES:	NA.72

trans-Zeatin has been used:

as a media supplement for the isolation and culture of pretransitional and transitional embryos
as a culture media supplement for incubating alginate strip culture
as a growth regulator in modified basal Murashige and Skoog medium

5, 10, 50, 250 mg in glass bottle

Zeatin upon reduction forms zeatin O-glucoside, which is widely present in plants. It possesses transportation and storage functions, along with defence against zeatin oxidases.
trans-Zeatin is a plant cytokinin

product line	BioReagent
assay	97%
application(s)	cell culture \| plant: suitable
Featured Industry	Agriculture
storage temp.	20°C
SMILES string	C\C(CO)=C/CNc1ncnc2nc[nH]c12
InChI	1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
InChI key	UZKQTCBAMSWPJD-FARCUNLSSA-N

Zeatin is a coconut milk-derived plant hormone (cytokinin) that promotes growth of lateral buds, stimulates cell division(Lateral Dominance), callus initiation and seed germination. Zeatin is used with Murashige and Skoog and other media, zeatin promotes multiple shoot generation from internodes and high frequency thick spread roots.

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Zeatin

Empirical Formula (Hill Notation):	C₁₀H₁₃N₅O
CAS Number:	13114-27-7
Molecular Weight:	219.24
MDL number:	MFCD00213654
PubChem Substance ID:	24902158
NACRES:	NA.72

1, 5, 10 mg in glass bottle
50, 250 mg in poly bottle
1 g in poly bottle

Primarly trans isomer: balance cis isomer

product line	BioReagent
form	powder
application(s)	cell culture \| plant: suitable
color	off-white to yellow
Featured Industry	Agriculture
storage temp.	−20°C
SMILES string	C\C(CO)=C/CNc1ncnc2[nH]cnc12
InChI	1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
InChI key	UZKQTCBAMSWPJD-FARCUNLSSA-N

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Bovine Calf Serum 13067C-1000ML

MDL number:

MFCD00243108

Bovine calf serum can sometimes be used as a cost effective alternative to fetal bovine serum, and is frequently used in large scale cell culture applications such as vaccine manufacturing.

Testing Method

Endotoxin and hemoglobin tested

SER-TAIN is a trademark of Sigma-Aldrich Co. LLC

Request a serum sample,

Legal Information

Quality Level	500,
biological source	bovine (calf)
sterility	-irradiated by SER-TAIN^™ process, sterile-filtered
composition	Hemoglobin, 35 mg/dL
origin	Australia origin
application(s)	cell culture \| mammalian: suitable
impurities	50 EU/mL Endotoxin
shipped in	dry ice
storage temp.	20°C

Donkey serum is pooled from a normal donor herd.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Complement C4 deficient serum from guinea pig

NACRES: NA.61

Кат. номер

C1038-1ML-PW

C1038-1ML

Application
Complement C4 deficiency has long been associated with the disease systemic lupus erythematosus (SLE) and severe kidney disorders. Screening of the mutations which lead to C4 deficiency may assist in studies of these diseases and disorders. It has been demonstrated that 40-60% of patients with SLE contained either heterozygous or homozygous deficiencies in C4 compliment components via C4A and C4B genes. In particular, research has shown that complete C4A and C4B deficiencies occur through deleterious mutations at exon 13 and within a 2.6-kb genomic region spanning exons 20-29.
Analysis Note
C4 is deficient as judged by a highly sensitive hemolytic assay and Ouchterlony immunodiffusion method.
Параметры

Quality Level 200,

biological source guinea pig

form solution

application(s) activity assay: suitable

shipped in dry ice

storage temp. −70°C

Safety Information

Personal Protective Equipment Eyeshields,, Gloves,

RIDADR NONH for all modes of transport

WGK Germany WGK 3

Flash Point F Not applicable

Flash Point C Not applicable

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Donkey serum

Normal donkey serum may be used as a blocking agent and controls in immunoassays. For immunohistochemistry and immunocytochemistry, donkey serum was used between 5%-20% as blocking agent in various studies.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source	donkey
Quality Level	200
sterility	non-sterile
contains	preservative
Featured Industry	Research Pathology
shipped in	dry ice
storage temp.	−20°C

Goat serum is pooled from a normal donor herd.

Pictograms	GHS07,GHS09
Signal Word	Warning
Hazard Statements	H315 - H317 - H319 - H411
Precautionary Statements	P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Goat serum

Normal goat serum may be used as a blocking agent or negative control in immunoassays. For immunohistochemistry and immunocytochemistry, goat serum was used between 1%-20% as blocking agent in various studies.
Goat serum has been used in:

immunohistochemistry
immunocytochemistry
double immunofluorescence
enzyme immunoassays (EIAs)

Goat serum can be effectively used for routine culture of fish cells.

Quality Level	200
biological source	goat
sterility	non-sterile
contains	preservative
Featured Industry	Research Pathology
shipped in	dry ice
storage temp.	−20°C

Guinea pig serum is pooled from normal donor herd.

Pictograms	GHS07,GHS09
Signal Word	Warning
Hazard Statements	H315 - H317 - H319 - H411
Precautionary Statements	P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
Personal Protective Equipment	Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Guinea pig serum

Guinea pig serum is suitable blocking agent and negative control in immunoassays.

Quality Level	200,
biological source	guinea pig
sterility	non-sterile
contains	preservative
shipped in	dry ice
storage temp.	−20°C

Horse serum displays homogeneity between fetal bovine serum and fetal calf serum .It has low levels of polyamine oxidase.
Horse serum is pooled from a normal donor herd.

pictograms	GHS07,GHS09
signalword	Warning
hcodes	H315 - H317 - H319 - H411
pcodes	P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Horse serum

Normal horse serum may be used as a blocking agent and controls in immunoassays. For immunohistochemistry and immunocytochemistry, 10% horse serum was used as blocking agent in various Studies.
Horse serum was used in immunostaining for blocking non-specific antibodies binding.
Horse serum has been used as a supplement in minimum essential medium for cerebrocortical neuronal−glial cell cultures and RPMI-40 medium for PC12 cells derived from rat adrenal medulla pheochromocytoma. It has also been used in immunohistochemistry of Florida manatee brain sections.

The horse serum is an alternative to bovine serum for growth factors and hormones for cell culture studies. Horse serum stimulates fibroblast differentiation and extracellular matrix (ECM) and cytokines synthesis.

biological source	horse serum
Quality Level	200,
sterility	non-sterile
form	liquid
contains	preservative
shipped in	dry ice
storage temp.	−20°C

Human AB serum is used in tissue engineering, transplantation and cell therapy applications for the expansion of mesenchymal stem cells (MSC) from adipose tissue or mesenchymal stromal cells from human bone marrow; for standardized limbal epithelial stem cell graft generation and transplantation; for ex vivo expansion of NK cells from peripheral blood in Hematopoeitic Stem Cell Expansion Medium; and for upgrading pretransplant human islet culture technology.

pictograms	GHS07,GHS09
signalword	Warning
hcodes	H315 - H317 - H319 - H411
pcodes	P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
Personal Protective Equipment	Eyeshields,, Gloves,
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Human Serum

MDL number:	MFCD00165829
NACRES:	NA.71

Warning

Each donor is tested for and found non-reactive for Hepatitis B & C and non-reactive for Human Immunodeficiency Virus (HIV) antibody by ELISA. Nevertheless, products of human origin should be considered potentially infectious and handled accordingly.

It is not unusual for our human serum products to be cloudy. This product is from pooled serum and cloudiness indicates that lipids are present in the serum. No clear, lipid-free human serum products are available.

biological source	human male plasma (Type AB)
sterility	sterile-filtered
composition	hemoglobin, ≤30 mg/dL
origin	USA origin
application(s)	cell culture \| mammalian: suitable, cell culture \| stem cell: suitable
impurities	≤10 EU/mL endotoxin
shipped in	dry ice
storage temp.	−20°C

Mouse serum acts as blocking agent in immunogold labeling, in vitro MBL-binding assays and in the evaluation of commercial estradiol immunoassays.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Mouse serum

10 mL in glass bottle

Quality Level	200
biological source	mouse
sterility	non-sterile
contains	preservative
shipped in	dry ice
storage temp.	20°C

Rabbit serum is pooled from a normal donor population.

Pictograms	GHS07,GHS09
Signal Word	Warning
Hazard Statements	H315 - H317 - H319 - H411
Precautionary Statements	P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
Personal Protective Equipment	Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Rabbit serum

Normal rabbit serum may be used as a blocking agent and controls in immunoassays. For immunohistochemistry and immunocytochemistry, 20% or 1:200 dilution of rabbit serum was used as blocking agent in various studies.

biological source	rabbit
Quality Level	200,
sterility	non-sterile
contains	preservative
conjugate	unconjugated
shipped in	dry ice
storage temp.	−20°C

Rat serum is pooled from a normal donor population.

pictograms	GHS07,GHS09
signalword	Warning
hcodes	H315 - H317 - H319 - H411
pcodes	P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Rat serum

Normal rat serum may be used as a blocking agent and controls in immunoassays.
for blocking agents and controls in immunoassays

biological source	rat
Quality Level	200,
sterility	non-sterile
contains	preservative
shipped in	dry ice
storage temp.	−20°C

Sheep serum can be used as a blocking agent and control in immunoassays. It has also been used to block non-specific reactivity in immunohistochemistry of frozen rat levator labii superioris muscle tissue sections.

pictograms	GHS07,GHS09
signalword	Warning
hcodes	H315 - H317 - H319 - H411
pcodes	P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Serum Replacement 2 (50)

NACRES: NA.71

Кат. номер

S9388-100ML

S9388-10ML

S9388-10ML-PW

S9388-100ML-PW

Other Notes
Defined, multi-purpose serum replacement with additional components for cells requiring higher concentrations of serum than 10%. Contains highly purified, heat-treated bovine serum albumin, heat-treated bovine transferrin and bovine insulin. Does not contain growth factors, steroid hormones, glucocorticoids, cell adhesion factors, detectable Ig and mitogens. May be used with anchorage-dependent and suspension cells.
Caution
Stable for 30 days when diluted in cell culture medium.
Параметры

biological source bovine

sterility sterile-filtered

form liquid

application(s) cell culture | mammalian: suitable

impurities endotoxin, tested

storage temp. 2-8°C

Safety Information

Personal Protective Equipment Eyeshields,, Gloves,

RIDADR NONH for all modes of transport

WGK Germany WGK 3

Flash Point F Not applicable

Flash Point C Not applicable

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Sheep serum

biological source	sheep
Quality Level	200,
sterility	non-sterile
contains	preservative
conjugate	unconjugated
shipped in	dry ice
storage temp.	−20°C

Cyclodextrins are cyclic oligosaccharides consisting of 6, 7, or 8 glucopyranose units, usually referred to as -, -, or -cyclodextrins, respectively. These compounds have rigid doughnut-shaped structures making them natural complexing agents. The unique structures of these compounds owe their stability to intramolecular hydrogen bonding between the C2- and C3-hydroxyl groups of neighboring glucopyranose units. The molecule takes on the shape of a torus with the C2- and C3-hydroxyls located around the larger opening and the more reactive C6-hydroxyl aligned around the smaller opening. The arrangement of C6-hydroxyls opposite the hydrogen bonded C2- and C3-hydroxyls forces the oxygen bonds into close proximity within the cavity, leading to an electron rich, hydrophobic interior. The size of this hydrophobic cavity is a function of the number of glucopyranose units forming the cyclodextrin.
The solubility of natural cyclodextrins is very poor. In the late 1960s, it was discovered that chemical substitutions at the 2, 3, and 6 hydroxyl sites would greatly increase solubility. Most chemically modified cyclodextrins are able to achieve a 50% (w/v) concentration in water.
Cavity size is the major determinant as to which cyclodextrin is used in complexation. The cavity diameter of -cyclodextrins or -glucopyranose unit compounds is well-suited for use with molecules the size of hormones, vitamins and many compounds frequently used in tissue and cell culture applications. For this reason, -cyclodextrin is most commonly used as a complexing agent.

pictograms	GHS07,GHS09
signalword	Warning
hcodes	H315 - H317 - H319 - H411
pcodes	P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
Personal Protective Equipment	Eyeshields,, Gloves,
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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(2-Hydroxypropyl)--cyclodextrin

CAS Number:	128446-35-5
EC Number:	420-920-1
PubChem Substance ID:	24892288
NACRES:	NA.77

5, 10 g in poly bottle

The solubility of lipophilic drugs increases linearly with the concentration of hydroxypropyl-β-cyclodextrin (HBC) in aqueous solution because of the complex between HBC and the drug. This guest-host type complex is formed between the drug and the non-polar cavity in the HBC that results in enhanced solubility. Solutions may be lyophilized to produce freely soluble powders. Non-toxic in rabbits and mice.

Solutions may be stored for several months at 4°C. Solid should be stored tightly sealed at room temperature.

biological source	corn starch
Quality Level	200
product line	BioReagent
form	powder
mol wt	1396 Da
extent of labeling	4-10 (determined by NMR)
application(s)	cell culture \| mammalian: suitable
solubility	H₂O: 100 mg/mL
shipped in	ambient
storage temp.	room temp
SMILES string	CC(O)COCC1OC2OC3C(COCC(C)O)OC(OC4C(COCC(C)O)OC(OC5C(COCC(C)O)OC(OC6C(COCC(C)O)OC(OC7C(COCC(C)O)OC(OC8C(COCC(C)O)OC(OC1C(OCC(C)O)C2OCC(C)O)C(OCC(C)O)C8OCC(C)O)C(OCC(C)O)C7OCC(C)O)C(OCC(C)O)C6OCC(C)O)C(OCC(C)O)C5OCC(C)O)C(OCC(C)O)C4OCC(C)O)C(OCC(C)O)C3OCC(C)O
InChI	1S/C63H112O42/c1-22(64)8-85-15-29-50-36(71)43(78)57(92-29)100-51-30(16-86-9-23(2)65)94-59(45(80)38(51)73)102-53-32(18-88-11-25(4)67)96-61(47(82)40(53)75)104-55-34(20-90-13-27(6)69)98-63(49(84)42(55)77)105-56-35(21-91-14-28(7)70)97-62(48(83)41(56)76)103-54-33(19-89-12-26(5)68)95-60(46(81)39(54)74)101-52-31(17-87-10-24(3)66)93-58(99-50)44(79)37(52)72/h22-84H,8-21H2,1-7H3/t22?,23?,24?,25?,26?,27?,28?,29-,30-,31?,32?,33?,34?,35?,36?,37-,38?,39-,40+,41+,42+,43?,44+,45?,46+,47+,48+,49+,50+,51+,52-,53-,54-,55-,56-,57+,58-,59+,60-,61-,62-,63-/m1/s1
InChI key	ODLHGICHYURWBS-RYJYQAAZSA-N

β-Cyclodextrin(β-CD) has been used in the synthesis of mono-6-tosyl-CD. It has also been used as a constituent in the serum-free medium to assess the involvement of cholesterol-dependent mechanisms in the uptake of nanoparticles by rat basophilic leukemia cells.

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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-Cyclodextrin

Empirical Formula (Hill Notation):	C₄₂H₇₀O₃₅
CAS Number:	7585-39-9
Molecular Weight:	1134.98
Beilstein/REAXYS Number:	78623
EC Number:	231-493-2
MDL number:	MFCD00078139
PubChem Substance ID:	24892728
NACRES:	NA.77

5, 25, 100 g in poly bottle

β-Cyclodextrin is the cyclic α heptamer of glucose. It acts as a host to form inclusion compounds with the guests including derivatives of benzene, cyclohexane, adamantane, other alicyclic guests, and also inorganic molecules or ions. It is generally used to solubilize non-polar compounds such a fatty acids, lipids and cholesterol.

sterility	non-sterile
Quality Level	200,
product line	BioReagent
assay	97%
form	powder
optical activity	[]20/D +162±3°, c = 1.5% in H₂O
application(s)	cell culture \| mammalian: suitable
mp	290-300 °C (dec.) (lit.)
solubility	1 M NaOH: 50 mg/mL
shipped in	ambient
storage temp.	room temp
SMILES string	OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)[C@H](O[C@@H]4CO)O[C@H]5[C@H](O)[C@@H](O)[C@H](O[C@@H]5CO)O[C@H]6[C@H](O)[C@@H](O)[C@H](O[C@@H]6CO)O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]1[C@H](O)[C@H]2O
InChI	1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1
InChI key	WHGYBXFWUBPSRW-FOUAGVGXSA-N

Adenine is a purine nucleobase, synthesized from inosine monophosphate(IMP). It is a nitrogenous heterocyclic aromatic compound.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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Adenine

Empirical Formula (Hill Notation):	C₅H₅N₅
CAS Number:	73-24-5
Molecular Weight:	135.13
Beilstein/REAXYS Number:	5777
EC Number:	200-796-1
MDL number:	MFCD00041790
PubChem Substance ID:	24890691
NACRES:	NA.75

Adenine has been used:

a component of green medium used for the derivation of keratinocytes from plucked hair follicles
for the serial culture of adult murine keratinocytes
as a media component for SSEA4+ limbal stromal stem cell differentiation

5, 25, 100 g in poly bottle

Adenine is a component of important biomolecules such as adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). NAD and FAD forms the structure of DNA and RNA, and plays important role in protein synthesis. ATP is an energy source, that is essential for cellular respiration.

Quality Level	200
biological source	synthetic
product line	BioReagent
assay	99%
form	powder
mol wt	M_w 135.13 g/mol
application(s)	cell culture \| mammalian: suitable
color	white to off-white
mp	>360 °C (lit.)
solubility	0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.	room temp
SMILES string	Nc1ncnc2[nH]cnc12
InChI	1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)
InChI key	GFFGJBXGBJISGV-UHFFFAOYSA-N
Gene Information	human ... AKT1(207), GSK3B(2932), LCK(3932), MAP3K1(4214), MAPK14(1432), MAPK8(5599), MAPK9(5601), MAPKAPK2(9261), PRKACA(5566), PRKCA(5578), RAF1(5894), ROCK2(9475) mouse ... Mapk1(26413) rat ... Camk2a(25400), Mapk10(25272)

Adenine hydrochloride hydrate has been used:

Pictograms	GHS06
Signal Word	Danger
Hazard Statements	H301
Precautionary Statements	P264 - P270 - P301 + P310 - P405 - P501
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3

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Adenine hydrochloride hydrate

Empirical Formula (Hill Notation):	C₅H₅N₅ · HCl · xH₂O
CAS Number:	2922-28-3
Molecular Weight:	171.59 (anhydrous basis)
MDL number:	MFCD00150864
PubChem Substance ID:	24891498
NACRES:	NA.75

As a component of FAD cell culture media
In maintaining organotypic cultures for recreating stratified epithelium from primary cell cultures
In limbal-corneal epithelial culturing and keratinocytes

1, 5, 25 g in poly bottle

biological source	synthetic (organic)
Quality Level	200,
product line	BioReagent
assay	99%
form	powder
application(s)	cell culture \| mammalian: suitable
solubility	H₂O: 50 mg/mL
SMILES string	O.Cl.Nc1ncnc2[nH]cnc12
InChI	1S/C5H5N5.ClH.H2O/c6-4-3-5(9-1-7-3)10-2-8-4;;/h1-2H,(H3,6,7,8,9,10);1H;1H2
InChI key	MYRDTAUFFBYTHA-UHFFFAOYSA-N

Aminopterin has been used in the production of anti- neurogranin antibodies.

Personal Protective Equipment	Eyeshields,, Gloves,, type N95 (US),
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Aminopterin

Empirical Formula (Hill Notation):	C₁₉H₂₀N₈O₅
CAS Number:	54-62-6
Molecular Weight:	440.41
Beilstein/REAXYS Number:	69045
EC Number:	200-209-9
PubChem Substance ID:	24890768
NACRES:	NA.75

Folic acid antagonist. Aminopterin is actively transported into cells by the folate transporter. In the cell, it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase that, in turn, binds to dihydrofolate reductase and inhibits its activity. Aminopterin-polyglutamate is degraded intracellularly by γ-glutamyl hydrolase.
Aminopterin is found to inhibit growth, embryogenesis and has toxic effects in mice models. It serves as a abortifacient. Aminopterin is known to reduce the effects of acute leukemia in children.

More potent, but more toxic, than methotrexate.

biological source	synthetic (organic)
Quality Level	200,
product line	BioReagent
assay	97%
form	powder
application(s)	cell culture \| mammalian: suitable
color	yellow
solubility	2 M NaOH: 50 mg/mL, DMSO: soluble
(extinction coefficient)	24,500 at 282 nm in 0.1 M NaOH at 1 M, 25,700 at 261 nm in 0.1 M NaOH at 1 M, 8,100 at 373 nm in 0.1 M NaOH at 1 M
shipped in	dry ice
storage temp.	20°C
SMILES string	Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
InChI	1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)/t12-/m0/s1
InChI key	TVZGACDUOSZQKY-LBPRGKRZSA-N
Gene Information	human ... FPGS(2356) mouse ... Fpgs(14287)