Anti-Mouse IgG (whole molecule)Agarose antibody produced in goat

MDL number:	MFCD03791275
NACRES:	NA.46

Кат. номер

A6531-25ML

A6531-5ML

A6531-2ML

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. Mice consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice. Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies bind to all mouse IgG subclasses.
IgG isolated from pooled normal mouse serum
Soluble antigens from meningococci extracts were mixed with ascitic fluid containing primary antibody and 50 μl of agarose-linked goat anti-mouse IgG for 5 hours at 4 °C.
Goat Anti-Mouse IgG (whole molecule)-Agarose antibodies have been used for immunoprecipiation assays. The product can also be used for Ouchterlony double diffusion applications.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper),
Immunoprecipitation (1 paper),
Packaging
2, 5, 25 mL in glass bottle
Biochem/physiol Actions
IgG helps in opsonization, complement fixation and antibody-dependent cell-mediated cytotoxicity. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. IgG2a of IgG has cytotropic properties and IgG2 molecules have the ability to activate complement.
Physical form
Suspension in 0.5 M NaCl containing preservative
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

biological source	goat
Quality Level	200,
antibody form	affinity isolated antibody
antibody product type	secondary antibodies
clone	polyclonal
form	suspension
species reactivity	mouse
extent of labeling	≥5 mg per mL
application(s)	Ouchterlony double diffusion: suitable, immunoprecipitation (IP): suitable
matrix	Cross-linked 4% beaded agarose
matrix activation	cyanogen bromide
matrix spacer	1 atom
capacity	0.4 mg/mL, resin binding capacity (mouse IgG)
conjugate	agarose conjugate
storage temp.	2-8°C

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3