Anti-Rabbit IgG (H+L), CF™ 647 antibody produced in goat

NACRES:

NA.46

Кат. номер

SAB4600184-50UL

SAB4600184-250UL

Antibody CF™ 647 conjugates are affinity-purified antibodies labeled with a far-red fluorescent dye, CF647. CF™ 647 conjugates are useful as secondary antibodies for detection.
Immunoglobulin G (IgG) is a major class of immunoglobulin family. It contains gamma () heavy chain in the constant (C) region and is a largely expressed serum antibody. Monomeric structure of IgG contains two identical heavy chains and two identical light chains with molecular weight of 50kDa and 25kDa respectively. The primary structure of this antibody also contains disulfide bonds involved in linking the two heavy chains, linking the heavy and light chains and resides inside the chains. IgG has four sub classes namely, IgG1, IgG2, IgG3, and IgG4 with different heavy chains, named 1,2, 3, and 4, respectively. IgG is produced and released from CD5+B cells, the predominant lymphocytes in the neonatal cell repertoire. Maternal IgG is the only antibody transported across the placenta to the fetus. Maternal IgG passively immunizes the infants.
Specificity
Binds all rabbit IgGs
rabbit IgG (H+L)
Anti-Rabbit IgG (H+L), CF™ 647 antibody produced in goat has been used as a secondary antibody in sections post terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) analysis of apoptotic cells. It has also been used in immunohistochemical staining at a dilution of 1/1,000.
Features and Benefits
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Physical form
Supplied in phosphate buffered saline with 0.05% sodium azide, 50% glycerol and 2 mg/mL bovine serum albumin.
Preparation Note
Protect from light.
This product is distributed by Sigma-Aldrich Co. under the authorization of Biotium, Inc. This product is covered by one or more US patents and corresponding patent claims outside the US patents or pending applications owned or licensed by Biotium, Inc. including without limitation: 12/334,387; 12/607,915; 12/699,778; 12/850,578; 61/454,484. In consideration of the purchase price paid by the buyer, the buyer is hereby granted a limited, non-exclusive, non-transferable license to use only the purchased amount of the product solely for the buyers own internal research in a manner consistent with the accompanying product literature. Except as expressly granted herein, the sale of this product does not grant to or convey upon the buyer any license, expressly, by implication or estoppel, under any patent right or other intellectual property right of Biotium, Inc. Buyer shall not resell or transfer this product to any third party, or use the product for any commercial purposes, including without limitation, any diagnostic, therapeutic or prophylactic uses. This product is for research use only. Any other uses, including diagnostic uses, require a separate license from Biotium, Inc. For information on purchasing a license to use this product for purposes other than research, contact Biotium, Inc., 3159 Corporate Place, Hayward, CA 94545, Tel: (510) 265-1027. Fax: (510) 265-1352. Email: btinfo@biotium.com.
CF is a trademark of Biotium, Inc.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Quality Level	100,
biological source	goat
antibody form	affinity isolated antibody
antibody product type	secondary antibodies
clone	polyclonal
form	buffered aqueous solution
species reactivity	rabbit
concentration	~2 mg/mL
application(s)	flow cytometry: 1-10 µg/mL, immunocytochemistry: suitable, immunohistochemistry: suitable, indirect immunofluorescence: 1-10 µg/mL
fluorescence	ex 650 nm; em 665 nm
conjugate	CF™ 647 conjugate
shipped in	dry ice
storage temp.	20°C

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable