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Recombinant Trypsin Dimethlyated
NACRES: NA.26
Кат. номер EMS0007-4X100UG EMS0007-PH EMS0007-100UG General descriptionTrypsin is routinely used in proteomics research for peptide mapping and protein sequence work due to its highly specific cleavage resulting in a limited number of tryptic peptides. Trypsin is a pancreatic serine endoprotease which hydrolyzes peptide bonds specifically at the carboxyl side of arginine and lysine residues. The rate of hydrolysis is slower if an acidic residue is on either side of the cleavage site and cleavage may not occur if a proline residue is on the carboxyl side. The enzyme also exhibits esterase and amidase activities. Trypsin has an average molecular mass of 23.29 kDa and a pH optimum near 8.0.
This product is prepared from recombinant trypsin, porcine sequence and the lysine residues have been dimethylated to further restrict autolysis. It is naturally devoid of chymotryptic activity. This high quality trypsin is suitable for proteomics use.
Specific activity: >= 10,000 BAEE units per mg protein.ПараметрыQuality Level 200 recombinant expressed in Pichia pastoris assay 10,000 unit/mg form lyophilized powder suitability suitable for mass spectrometry UniProt accession no. P00761, shipped in wet ice storage temp. 2-8°C
Safety Informationpictograms GHS05,GHS07,GHS08,GHS09 signalword Danger hcodes H290 - H314 - H317 - H332 - H334 - H335 - H411 pcodes P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 Target Organs Respiratory system Supp Hazards EUH071 RIDADR UN 1789 8 / PGIII WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SigmaMAb Antibody Drug Conjugate (ADC) Mimic
Кат. номер MSQC8-PH MSQC8-0.5MG General descriptionSigmaMab Antibody Drug Conjugate (ADC) Mimic, is a non-toxic drug mimic that is utilized as a standard for mass spectrometry and high performance liquid chromatography. The ADC Mimic conjugates SigmaMab (MSQC4), an IgG1 monoclonal antibody, to dansyl fluorophores via an LC-SMCC crosslinker. This dansyl-LC-SMCC attachment serves as the substitution for the toxic payload of a real ADC.
The ADC Mimic allows for safer and more consistent testing, making it the optimal product over real ADCs. It is also a more affordable product compared to real ADCs. With the help of this non-toxic product, LC-MS processes can be developed in a safer environment.ApplicationPoster: Antibody Drug Conjugate Mimic Enables LC-MS Method Development Without Risk
Poster: LC-UV-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC-Mimic
Poster: LC-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC MimicПараметрыQuality Level 200 recombinant expressed in CHO cells antibody product type primary antibodies form lyophilized powder shipped in wet ice storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SigmaProt Intact Protein LC-MS Standard
EC Number: 220-163-3 NACRES: NA.24
Кат. номер MSRT2-PH MSRT2-1VL MSRT2-1VL-PW MSRT1-1VL-PW MSRT2-5X1VL ApplicationThe RP-LC-MS Protein Standard is a LC-MS platform standard that is intended to test LC-MS system suitability and intact protein mass measurement. The proteins in MSRT2 are chosen to represent an elution profile for complex proteomic samples. The proteins have been selected based on UV and electrospray response, and are readily observed by both modes of detection. After reconstitution, MSRT2 is an injection-ready standard. MSRT2 can be utilized in studies such as in top-down proteomics.
Components
MSRT2 contains these 9 proteins:- Ribonuclease B
- Insulin
- Lysozyme
- Transferrin
- Bovine serum albumin (BSA)
- Trypsin inhibitor
- -lactoglobulin A
- Carbonic anhydrase
- Lactate dehydrogenase
ПараметрыQuality Level 200, storage temp. −20°C
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary A1(3) Sial(Alpha-2,3)
Empirical Formula (Hill Notation): C6513C8H121N5O54 Molecular Weight: 1940.68
Кат. номер ILGA13S23-600PMO ILGA13S23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary A1(6)F Sial(Alpha-2,3)
Empirical Formula (Hill Notation): C6513C8H121N5O53 Molecular Weight: 1924.68
Кат. номер ILGA16FS23-600PMO ILGA16FS23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary A2 2x(Sial(Alpha-2,3))
Кат. номер ILGA22S23-600PMO ILGA22S23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary A2 2x(Sial(Alpha-2,6))
Кат. номер ILGA22S26-600PMO ILGA22S26-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary A2F 2x(Sial(Alpha-2,3))
Empirical Formula (Hill Notation): C8213C8H148N6O66 Molecular Weight: 2378.08
Кат. номер ILGA2F2S23-600PMO ILGA2F2S23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary A2F 2xSial(Alpha-2,6)
Empirical Formula (Hill Notation): C8213C8H148N6O66 Molecular Weight: 2378.08
Кат. номер ILGA2F2S26-600PMO ILGA2F2S26-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary bA2F 2xSial(Alpha-2,6)
Empirical Formula (Hill Notation): C8213C8H148N6O66 Molecular Weight: 2378.08
Кат. номер ILBA2F2S26-600PMO ILBA2F2S26-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary bG0
Empirical Formula (Hill Notation): C4813C10H97N5O41 Molecular Weight: 1530.33
Кат. номер ILGBG0-600PMO ILGBG0-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G0
Empirical Formula (Hill Notation): C4213C8H84N4O36 Molecular Weight: 1325.15
Кат. номер ILGG0-600PMO ILGG0-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G0F
Empirical Formula (Hill Notation): C8213C8H148N6O66 Molecular Weight: 2378.08
Кат. номер ILGG0F-600PMO ILGG0F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G1(3)
Empirical Formula (Hill Notation): C4813C8H94N4O41 Molecular Weight: 1487.29
Кат. номер ILGG13-600PMO ILGG13-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G1(6)
Empirical Formula (Hill Notation): C4813C8H94N4O41 Molecular Weight: 1487.29
Кат. номер ILGG16-2000PMO ILGG16-600PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G1(6)F
Empirical Formula (Hill Notation): C5413C8H104N4O45 Molecular Weight: 1633.43
Кат. номер ILGG16F-600PMO ILGG16F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2
Empirical Formula (Hill Notation): C5413C8H104N4O46 Molecular Weight: 1649.43
Кат. номер ILGG2-600PMO ILGG2-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(3) Sial(Alpha-2,3)
Empirical Formula (Hill Notation): C6513C8H121N5O54 Molecular Weight: 1940.68
Кат. номер ILG2A13S23-600PMO ILG2A13S23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(3) Sial(Alpha-2,6)
Empirical Formula (Hill Notation): C6513C8H121N5O54 Molecular Weight: 1940.68
Кат. номер ILG2A13S26-600PMO ILG2A13S26-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(6) Sial(Alpha-2,3)
Empirical Formula (Hill Notation): C6513C8H121N5O54 Molecular Weight: 1940.68
Кат. номер ILG2A16S23-600PMO ILG2A16S23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(6)F Sial(Alpha-2,3)
Empirical Formula (Hill Notation): C7113C8H131N5O58 Molecular Weight: 2086.83
Кат. номер IL2A16FS23-600PMO IL2A16FS23-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2A1(6)F Sial(Alpha-2,6)
Empirical Formula (Hill Notation): C7113C8H131N5O58 Molecular Weight: 2086.83
Кат. номер IL2A16FS26-600PMO IL2A16FS26-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Biantennary G2F
Empirical Formula (Hill Notation): C6013C8H114N4O50 Molecular Weight: 1795.57
Кат. номер ILGG2F-600PMO ILGG2F-2000PMO Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Paucimannose Man3
Empirical Formula (Hill Notation): C3013C4H58N2O26 Molecular Weight: 914.79
Кат. номер ILGM3-600PMO ILGM3-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Paucimannose Man5
Empirical Formula (Hill Notation): C4213C4H78N2O36 Molecular Weight: 1239.07
Кат. номер ILGM5-600PMO ILGM5-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G0
Empirical Formula (Hill Notation): C6013C6H110N6O46 Molecular Weight: 1729.55
Кат. номер ILGA4G0-600PMO ILGA4G0-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G1a
Empirical Formula (Hill Notation): C6613C6H120N6O51 Molecular Weight: 1891.69
Кат. номер ILGA4G1A-600PMO ILGA4G1A-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G1c
Empirical Formula (Hill Notation): C6613C6H120N6O51 Molecular Weight: 1891.69
Кат. номер ILGA4G1C-600PMO ILGA4G1C-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G1d
Empirical Formula (Hill Notation): C6613C6H120N6O51 Molecular Weight: 1891.69
Кат. номер ILGA4G1D-600PMO ILGA4G1D-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G3abd
Empirical Formula (Hill Notation): C7813C6H140N6O61 Molecular Weight: 2215.97
Кат. номер ILGA4G3ABD-600PMO ILGA4G3ABD-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G3bcd
Empirical Formula (Hill Notation): C7813C6H140N6O61 Molecular Weight: 2215.97
Кат. номер ILGA4G3BCD-600PMO ILGA4G3BCD-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G4
Empirical Formula (Hill Notation): C8413C6H150N6O66 Molecular Weight: 2378.11
Кат. номер ILGA4G4-600PMO ILGA4G4-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G4-LacNAc
Empirical Formula (Hill Notation): C9813C6H173N7O76 Molecular Weight: 2743.44
Кат. номер ILGA4NALG4-600PMO ILGA4NALG4-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Tetraantennary A4G4F-LacNAc
Empirical Formula (Hill Notation): C10413C6H183N7O80 Molecular Weight: 2889.58
Кат. номер ILA4NALG4F-600PMO ILA4NALG4F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Triantennary G0
Empirical Formula (Hill Notation): C4813C10H97N5O41 Molecular Weight: 1530.33
Кат. номер ILGA3G0-600PMO ILGA3G0-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Triantennary G0F
Empirical Formula (Hill Notation): C5413C10H107N5O45 Molecular Weight: 1676.47
Кат. номер ILGA3G0F-600PMO ILGA3G0F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C Triantennary G3F
Empirical Formula (Hill Notation): C7213C10H137N5O60 Molecular Weight: 2162.89
Кат. номер ILGA3G3F-600PMO ILGA3G3F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C truncated MGn(3)F
Empirical Formula (Hill Notation): C4213C6H81N3O35 Molecular Weight: 1266.11
Кат. номер ILGMGN3F-600PMO ILGMGN3F-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Carb Glycan Standard 13C truncated MGn(6)
Empirical Formula (Hill Notation): C3613C6H71N3O31 Molecular Weight: 1119.97
Кат. номер ILGMGN6-600PMO ILGMGN6-2000PMO General descriptionSILu™Carb Glycan Standards are patented synthetic 13C-labeled N-glycans for use as internal standards in absolute glycan quantification by mass spectrometry.ApplicationFor use as a quantitative standard in applications such as Matrix-assisted Laser Desorption Ionization-time-of-flight (MALDI-TOF), Electrospray Ionization (ESI) and Liquid Chromatography Mass Spectrometry (LC-MS).
Physical form
13C labeled N-glycan refernce standard. 20 microM quantified solutionLegal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыshipped in ambient storage temp. 2-8°C
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™CHOP Stable-Isotope Labeled CHO Proteins
Кат. номер MSQC12-PH MSQC12-100UG General descriptionContamination of final product with Host Cell Proteins (HCPs) is a major concern for the development and production of Biotherapeutics in CHO cell lines. SILuCHOP is a representative heavy-isotope labeled standard of secreted host cell proteins, thus facilitating identification of biotherapeutics with contaminant host cell proteins by mass spectrometry.Legal InformationThis product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200, packaging vial of 100 µg suitability suitable for , suitable for mass spectrometry shipped in wet ice storage temp. 20°C
Safety Informationpictograms GHS05 signalword Danger hcodes H290 - H314 pcodes P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310 RIDADR UN 1824 8 / PGII WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite AKT1, RAC-alpha serine/threonine-protein kinase human
NACRES: NA.12
Кат. номер MSST0050-50UG MSST0050-50UG-PW General descriptionSILu™Lite AKT1 is a recombinant human protein expressed in human 293 cells. It consists of 501 amino acids, with a calculated molecular mass of 58.2 kDa (including N-terminal polyhistidine and flag tags). SILu™Lite AKT1 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Sequence
MDYKDDDDKGHHHHHHHHGGQMSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
Physical form
Supplied as a liquid containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form liquid suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P31749, shipped in dry ice storage temp. 20°C Gene Information human ... AKT1(207)
Safety InformationRIDADR NONH for all modes of transport Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite AKT2, RAC-beta serine/threonine-protein kinase human
NACRES: NA.12
Кат. номер MSST0052-50UG MSST0052-50UG-PW General descriptionSILu™Lite AKT2 is a recombinant human protein expressed in human 293 cells. It consists of 502 amino acids, with a calculated molecular mass of 58.2 kDa (including N-terminal polyhistidine and flag tags). SILu™ AKT2 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Sequence
MDYKDDDDKGHHHHHHHHGGQMNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIRE
Physical form
Supplied as a liquid containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form liquid suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P31751, shipped in dry ice storage temp. 20°C Gene Information human ... AKT2(208)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite AKT3, RAC-gamma serine/threonine-protein kinase human
NACRES: NA.12
Кат. номер MSST0054-50UG MSST0054-50UG-PW General descriptionSILu™Lite AKT3 is a recombinant human protein expressed in human 293 cells. It consists of 500 amino acids (including N-terminal polyhistidine and flag tags), with a calculated molecular mass of 58.2 kDa. SILu™Lite AKT3 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Sequence
MDYKDDDDKGHHHHHHHHGGQMSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQLMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
Physical form
Supplied as a liquid containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form liquid conjugate His tagged suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. Q9Y243, shipped in dry ice storage temp. 20°C Gene Information human ... AKT3(10000)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite ALB Albumin human
NACRES: NA.12
Кат. номер MSST0012-50UG MSST0012-50UG-PW General descriptionSILu™Lite ALB is a recombinant human protein expressed in human 293 cells. It is a monomer of 607 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~69 kDa. SILu™Lite ALB is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Biochem/physiol Actions
Albumin is synthesized exclusively by the liver parenchymal cells at a rate of 14 g/day. While it is the most abundant plasma protein (>50%), increased urine albumin concentrations indicate bleedings in the lower urinary tract (ureter, bladder) or infections of the renal pelvis. A small abnormal albumin excretion is known as Microalbuminuria and serves as an indicator for temporary overload of the glomerular filtration (fever, excessive sports) or chronic injury of the glomeruli (diabetes).
Sequence
RRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGLDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationThis product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P02768, shipped in ambient storage temp. 20°C Gene Information human ... ALB(213)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite AMBP Alpha-1 Microglycoprotein human
NACRES: NA.12
Кат. номер MSST0014-50UG MSST0014-50UG-PW General descriptionSILu™ Lite AMBP is a recombinant human protein expressed in human 293 cells. It is a monomer of 204 amino acids (including C-terminal polyhistidine and flag tags), with a molecular weight of ~23 kDa. SILu™ Lite AMBP is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Biochem/physiol Actions
AMBP is synthesized by the liver. Approximately half of the circulating protein is complexed to IgA. The free form of AMBP is filtered by the glomerulus and reabsorbed by proximal tubule cells. AMBP has been found to be a sensitive biomarker for proximal tubular dysfunction even in the early phase of injury when no histologic damage is observable. In addition, urinary AMBP has been proposed to be a useful marker of tubular dysfunction even in low-gestational-age preterm infants, a population at high risk for AKI (Acute Kidney Injury). Urinary AMBP is also a marker of kidney damage in type 2 diabetes.
Sequence
GPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIMDRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMESYVVHTNYDEYAIFLTKKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIFTMADRGECVPGEQEPEPILIPRVDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationThis product is licensed under U.S. Patent No. 7,396,688 and foreign counterparts from E. I. du Pont de Nemours and Company. The purchase of this product conveys to the buyer the nontransferable right to use the purchased amount of the product for research and development only, including services for a third party for consideration. The buyer cannot sell or otherwise transfer this product, its components or materials made using this product or its components to a third party. Information about licenses for excluded uses is available from: E. I. du Pont de Nemours and Company; Attn: Associate Director, Commercial Development; DuPont Experimental Station E268; 200 Powdermill Rd.; Wilmington, DE 19803; 1-877-881-9787 (voice), 1-302-695-1437 (fax), licensing@dupont.com.
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder application(s) mass spectrometry (MS): suitable conjugate His tagged suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P02760, storage temp. 20°C Gene Information human ... AMBP(259)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite APOA1 Apolipoprotein A-1 human
Кат. номер MSST0002-50UG MSST0002-50UG-PW
Biochem/physiol Actions
Apolipoprotein A-1(Apo-A1), is a major protein component of high density lipoprotein (HDL)in plasma1. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters2. Apo-A1 was shown to assist in the improvement of predicting cardiovascular events3. The gene that encodes to Apolipoprotein A-1 is APOA1. This gene is closely linked with two other apolipoprotein genes on chromosome 114. Defects in this gene are associated with HDL deficiencies, including Tangier disease5, and with systemic non-neuropathic amyloidosis6. The protein is made up of one major isoform (pI 5.6) and two minor isoforms (pI 5.53 and 5.46). Apo-A1 shows a high content of a-helix structure6. The amphipathic regions in the -helix structure seem to be responsible for lipid binding capacity. In aqueous solution, Apo-A1 shows self-association with minor conformational change7. In addition, it has been shown that Apo-A1 is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin8.
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.
Analysis Note
General Description
SILuLite APOA1 is a recombinant human protein expressed in human 293 cells. It is a monomer of 286 amino acids (including N-terminal signal sequence and C-terminal polyhistidine and V5 tags), with a molecular weight of 32.1 kDa. SILuLite APOA1 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Sequence
RHFWQQDEPPQSPWDRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQSDPSRGPFEGKPIPNPLLGLDSTRTGHHHHHHHHGGQ
The N-terminal signal peptide and C-terminal linker peptide, V5 and polyhistidine tags are italicized.
Other Characterization- Sequence confirmed by intact mass analysis
- Identity verified by peptide mapping
- purity >98% (SDS-PAGE)
- Vial content was determined by the Bradford method using BSA as a calibrator. The correction factor of Bradford-to-AAA is 88.33%
Suggested Quantitative Analysis Parameters
(MRM settings provided for three suggested peptides,)Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder packaging vial of 50-65 µg (Lot-specific vial content given on certificate of analysis) application(s) mass spectrometry (MS): suitable conjugate His tagged","V5 tagged UniProt accession no. P02647, storage temp. 20°C Gene Information human ... APOA1(335)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 3 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite APOA2 Apolipoprotein A-II human
NACRES: NA.12
Кат. номер MSST0030-50UG MSST0030-50UG-PW General descriptionApolipoprotein A-II (ApoA-II) occurs in plasma as a dimer of two 77-amino acid chains linked by a disulfide bridge. After apoA-I, it is the second major protein component of HDL, accounting for approximately 20% of HDL total protein. ApoA-II is thought to play an important role in triglyceride metabolism both from animal and human studies. 3 Recent findings attribute apoA-II to inhibitory effects on lipoprotein lipase-mediated hydrolysis of triglyceride-rich particles. Additional associations of apoA-II have been reported for a variety of protein factors including hepatic lipase (HL), lipoprotein lipase (LPL), endothelial lipase, CETP, PLTP, and LCAT.ImmunogenMAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGLDRIRGRKLGPFEGKPIPNPLLGLDSTRTGHHHHHHHHGGQ
Biochem/physiol Actions
SILu™Lite APOA2 is a recombinant human protein expressed in human 293 cells. It is a homodimer consisting of 97 amino acids (including C-terminal polyhistidine and flag tags), with a calculated molecular mass of 11 kDa. SILu Lite APOA2 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Physical form
Supplied as a lyophilized powder containing phosphate buffered saline.Legal InformationSILu is a trademark of Sigma-Aldrich Co. LLCПараметрыQuality Level 200 biological source human recombinant expressed in HEK 293 cells assay 98% (SDS-PAGE) form lyophilized powder potency 98 Heavy amino acids incorporation efficiency by MS application(s) mass spectrometry (MS): suitable suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P02652, storage temp. 20°C Gene Information human ... APOA2(336)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 2 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
SILu™Lite APOB48, Apolipoprotein B-48 human
NACRES: NA.32
Кат. номер MSST0056-50UG MSST0056-50UG-PW General descriptionSILu™Lite APOB48 is a recombinant human protein expressed in human 293 cells. It consists of 2172 amino acids, with a calculated molecular mass of 243.2 kDa (including C-terminal polyhistidine and flag tags). SILu™Lite APOB48 is an analytical standard designed to be used as starting material for preparation of calibrators and controls in LC-MS applications.
Apolipoprotein B 48 (APOB48) is a key subunit of APOB. APOB is encoded by the gene mapped to human chromosome 2p24.1.
Biochem/physiol Actions
Apolipoprotein B-48 (Apo B-48) is known to be the only specific marker of intestinal chylomicron (CM) particles. The amino acid sequence of apoB-48 represents 48% of the initial sequence of apolipoprotein B-100 (Apo B-100). Apo B-48 is synthesized only by the intestine in humans, while Apo B-100 is synthesized primarily by the liver. Therefore, Apo B-48 is a most appropriate biomarker for cardiovascular and nutritional investigation of postprandial CM metabolism.In a recent study, Apo B-48 was discovered as a novel biomarker in amyotrophic lateral sclerosis patient fibroblasts.
Apolipoprotein B 48 acts as a ligand for low-density lipoprotein (LDL)-receptor. Elevated levels of APOB is associated with the development of elevated LDL levels and other lipid metabolic disorders. In addition, overexpression of the gene increases the risk of susceptibility to coronary heart disease.
Sequence
EEEMLENVSLVCPKDATRFKHLRKYTYNYEAESSSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCTLKEVYGFNPEGKALLKKTKNSEEFAAAMSRYELKLAIPEGKQVFLYPEKDEPTYILNIKRGIISALLVPPETEEAKQVLFLDTVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPIRTGISPLALIKGMTRPLSTLISSSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKYGMVAQVTQTLKLEDTPKINSRFFGEGTKKMGLAFESTKSTSPPKQAEAVLKTLQELKKLTISEQNIQRANLFNKLVTELRGLSDEAVTSLLPQLIEVSSPITLQALVQCGQPQCSTHILQWLKRVHANPLLIDVVTYLVALIPEPSAQQLREIFNMARDQRSRATLYALSHAVNNYHKTNPTGTQELLDIANYLMEQIQDDCTGDEDYTYLILRVIGNMGQTMEQLTPELKSSILKCVQSTKPSLMIQKAAIQALRKMEPKDKDQEVLLQTFLDDASPGDKRLAAYLMLMRSPSQADINKIVQILPWEQNEQVKNFVASHIANILNSEELDIQDLKKLVKEALKESQLPTVMDFRKFSRNYQLYKSVSLPSLDPASAKIEGNLIFDPNNYLPKESMLKTTLTAFGFASADLIEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVNGQVPDGVSKVLVDHFGYTKDDKHEQDMVNGIMLSVEKLIKDLKSKEVPEARAYLRILGEELGFASLHDLQLLGKLLLMGARTLQGIPQMIGEVIRKGSKNDFFLHYIFMENAFELPTGAGLQLQISSSGVIAPGAKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQMNTNFFHESGLEAHVALKAGKLKFIIPSPKRPVKLLSGGNTLHLVSTTKTEVIPPLIENRQSWSVCKQVFPGLNYCTSGAYSNASSTDSASYYPLTGDTRLELELRPTGEIEQYSVSATYELQREDRALVDTLKFVTQAEGAKQTEATMTFKYNRQSMTLSSEVQIPDFDVDLGTILRVNDESTEGKTSYRLTLDIQNKKITEVALMGHLSCDTKEERKIKGVISIPRLQAEARSEILAHWSPAKLLLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMTSNFPVDLSDYPKSLHMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQKASGSLPYTQTLQDHLNSLKEFNLQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIPLPFGGKSSRDLKMLETVRTPALHFKSVGFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLSTNVYSNLYNWSASYSGGNTSTDHFSLRARYHMKADSVVDLLSYNVQGSGETTYDHKNTFTLSYDGSLRHKFLDSNIKFSHVEKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHLFVKEVKIDGQFRVSSFYAKGTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQSGIIKNTASLKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLRFFSLLSGSLNSHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTNLKCSLLVLENELNAELGLSGASMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNIFNFKVSQEGLKLSNDMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTVNLQLQPYSLVTTLNSDLKYNALDLTNNGKLRLEPLKLHVAGNLKGAYQNNEIKHIYAISSAALSASYKADTVAKVQGVEFSHRLNTDIAGLASAIDMSTNYNSDSLHFSNVFRSVMAPFTMTIDAHTNGNGKLALWGEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVSRKSISAALEHKVSALLTPAEQTGTWKLKTQFNNNEYSQDLDAYNTKDKIGVELTGRTLADLTLLDSPIKVPLLLSEPINIIDALEMRDAVEKPQEFTIVAFVKYDKNQDVHSINLPFFETLQEYFERNRQTIIVVLENVQRNLKHINIDQFVRKYRAALGKLPQQANDYLNSFNWERQVSHAKEKLTALTKKYRITENDIQIALDDAKINFNEKLSQLQTYMIDYKDDDDKGHHHHHHHHGGQ
Physical form
Supplied as a liquid containing phosphate buffered saline.Legal InformationFLAG is a registered trademark of Sigma-Aldrich Co. LLC
SILu is a trademark of Sigma-Aldrich Co. LLCПараметрыrecombinant expressed in HEK 293 cells Quality Level 200 assay 95% (SDS-PAGE) form liquid conjugate FLAG® tagged","His tagged suitability suitable for mass spectrometry (internal calibrator) UniProt accession no. P04114, shipped in dry ice storage temp. 20°C Gene Information human ... APOB48(338)
Safety InformationRIDADR NONH for all modes of transport WGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену
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